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RNA-seq data in cardiac tissues from cardiomyocyte-specific Acsl4 knockout mice after transverse aortic constriction

ABSTRACT: RNA-seq data in cardiac tissues from cardiomyocyte-specific Acsl4 knockout mice after transverse aortic constriction

PROVIDER: PRJEB79147 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR13511002_1.fastq.gz	Fastqsanger.gz
	ERR13511002_2.fastq.gz	Fastqsanger.gz
	ERR13511003_1.fastq.gz	Fastqsanger.gz
	ERR13511003_2.fastq.gz	Fastqsanger.gz
	ERR13511004_1.fastq.gz	Fastqsanger.gz

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RNA-seq data in cardiac tissues from cardiomyocyte-specific Acsl4 knockout mice after transverse aortic constriction

Project description:In order to investigate the differentially expressed genes in Acsl4 knockout after TAC (Transverse aortic constriction) or sham surgery. The experiment was divided to four groups including sham-operated Acsl4 flox/flox mice (FS), sham-operated Acsl4 knockout mice (KS), TAC-operated Acsl4 flox/flox mice (FT), TAC-operated Acsl4 knockout mice (KT) n=3 mice/group. The heart tissue was isolated after 21 days after performing TAC or sham surgery.

2024-08-26 | E-MTAB-14383 | biostudies-arrayexpress

Single-Cell Genomics of Transverse Aortic Constriction in Mouse

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Gene expression following transverse aortic constriction in mice housed under normoxic or hypoxic conditions

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The effect of transverse aortic constriction on gene expression in Balb/cJ versus Balb/cByJ(∆ACADS) mice hearts

Project description:RNA-Seq data show that ACADS knockout curbs gene expression after transverse aortic constriction in mice

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Proteomic Analysis Reveals Molecular Signatures of Myocardial Infarction and Transverse Aortic Constriction in Aged Mouse Models

Project description:Project description: In this study, we performed proteome analyses to identify the key molecules that participate in aged mouse models of MI and transverse aortic constriction (TAC), the latter of which mimics increased left ventricular afterload that in the clinical setting predominantly occurs owing to aortic stenosis or systemic hypertension. B11 represents the tissues of an aged MI mouse. B17 represents the tissues of an aged TAC mouse. B15 represents the tissues of an aged Sham mouse.

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2025-05-06 | PXD044254 | Pride

ACAA2 genome-binding patterns before and after transverse aortic constriction in C57Bl/6J mice on different diets [ACAA2]

Project description:Acetyl-CoA acyltransferace 2 (ACAA2) associates with chromatin at promoter sites in the heart of C57Bl/6J mice. A high-fat vs. low-fat diet reduces it promoter abundance, whereas, transverse aortic constriction (TAC) increases it slight.

2021-05-11 | GSE165284 | GEO

Proteome wide screening for ubiquitination, ISGylation and NEDDylation sites in wildtype and ISG15 knockout mouse hearts after transverse aortic constriction

Project description:Hearts(left ventricles) were harvested from control wildtype and ISG15 knockout mice and wildtype and ISG15 knockout mice 4 weeks after pressure overload induced by transverse aortic constriction. Nano LC-MS/MS analysis was performedon left ventricle tissue following protein extraction, trypsin digestion, peptide desalting, anti K-e-GG enrichment.

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Transcriptomic analysis of mice heart following transverse aortic constriction (TAC) surgery

Project description:Transcriptomic analysis of mice heart following transverse aortic constriction (TAC) surgery

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Transcription profiling of models of cardiac remodelling: myocardial infarction or transverse aortic constriction in left ventricle free wall and septum

Project description:We employed the Affymetrix GeneChip technology to evaluate the patterns of expression in two different in vivo models of cardiac remodeling and in two different regions (left ventricle free wall and septum) of the heart. Mice underwent transverse aortic constriction (TAC); myocardial infarction (MI) or Sham operation and RNA from the left ventricle free wall and the septum was isolated 1 week later.

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