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A study on the impact of the absence of the NIP or NrpR gene on gene expression of Streptococcus salivarius K12 (SAL)

ABSTRACT: A study on the impact of the absence of the NIP or NrpR gene on gene expression of Streptococcus salivarius K12 (SAL)

PROVIDER: PRJNA1039769 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR26804857.fastq.gz	Fastqsanger.gz
	SRR26804858.fastq.gz	Fastqsanger.gz
	SRR26804859.fastq.gz	Fastqsanger.gz
	SRR26804860.fastq.gz	Fastqsanger.gz
	SRR26804861.fastq.gz	Fastqsanger.gz

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A study on the impact of the absence of the NIP or NrpR gene on gene expression of Streptococcus salivarius K12 (SAL)

Project description:NIP and NrpR forms a pair for the transcriptional regulator in Streptococcus salivarius K12 (SAL). To explore the target genes regulated by the NIP-NrpR pair in Streptococcus salivarius K12 (SAL), we generated mutants in which the NIP or NrpR gene has been knocked down through complement recombination. Comparative transcriptome profiling of WT, ▲nrpR, and nip* mutant strains revealed that the sar BGC is the major regulatory target controlled by the NIP signaling pathway in SAL.

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