Project description:Microbial community diversity, assembly mechanism, and network changes before and after ecological water replenishment in spring 2024
Project description:The presence of numerous chemical contaminants from industrial, agricultural, and pharmaceutical sources in water supplies poses a potential risk to human and ecological health. Current chemical analyses suffer from limitations including chemical coverage and high cost, and broad-coverage in vitro assays such as transcriptomics may further improve water quality monitoring by assessing a large range of possible effects. Here, we used high-throughput transcriptomics to assess the activity induced by field-derived water extracts in MCF7 breast carcinoma cells.
Project description:Changes in microbial community diversity, assembly mechanism, and network of water bodies before and after ecological replenishment in spring 2024
| PRJEB98853 | ENA
Project description:Evolutionary and ecological dynamics of E. coli populations in long cycles of nutrient-replenishment
Project description:The ecological significance of light perception in non-phototrophic bacteria remains largely elusive. In terrestrial environments, diurnal oscillations in light are often temporally coupled to other environmental changes, including increased temperature and evaporation. Here we report that light functions as an anticipatory cue that triggers protective adaptations to tolerate a future rapid loss of environmental water in leaf-associated Pseudomonas syringae pv. syringae (Pss) and other terrestrial pseudomonads. Global transcriptome analyses in Pss showed that light control occurs almost entirely through a bacteriophytochrome photoreceptor that senses red, far-red and blue wavelengths and influences 30% of the Pss genome. Bacteriophytochrome-mediated light control disproportionally upregulates water-stress adaptation functions and confers enhanced fitness when cells encounter light prior to water limitation. These data demonstrate that non-phototrophic bacteria can use light as a cue to mount an adaptive anticipatory response against a physiologically unrelated but ecologically coupled stress.
Project description:We report that Zinc Replenishment Reverses Overexpression of the Proinflammatory Mediator S100A8 and Esophageal Preneoplasia in the Rat
