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Gut microbiota drives vitiligo-related oxidative stress in skin via the metabolite Hippuric Acid

ABSTRACT: Gut microbiota drives vitiligo-related oxidative stress in skin via the metabolite Hippuric Acid

PROVIDER: PRJNA1140852 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR30011300_1.fastq.gz	Fastqsanger.gz
	SRR30011300_2.fastq.gz	Fastqsanger.gz
	SRR30011301_1.fastq.gz	Fastqsanger.gz
	SRR30011301_2.fastq.gz	Fastqsanger.gz
	SRR30011302_1.fastq.gz	Fastqsanger.gz

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Gut microbiota drives vitiligo-related oxidative stress in skin via the metabolite Hippuric Acid

Project description:Vitiligo is a common autoimmune skin disorder. We constructed an induced vitiligo mouse model and performed bulk-RNA sequencing on the skin and 16S rRNA sequencing of feces from vitiligo mice and uninduced mice. Next, we performed skin bulk-RNA sequencing after treatment using ABX. Lastly, we subjected gut microbe-related metabolite hippuric acid to control mice and performed bulk-RNA sequencing on the skin to observe oxidative stress-related gene expression changes.

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