Project description:In this study, isobaric tags for relative and absolute quantification (iTRAQ) were used to identify differential expression proteins (DEPs) of adult schistosomes across two different intermediate host development: Oncomelania hupensis (O.hupensis) and Oncomelania weishan (O.weishan).
2022-10-24 | PXD035090 |
Project description:Temporal transcriptome response of Oncomelania hupensis by Schistosoma japonicum invasion
Project description:The Chinese sturgeon (Acipenser sinensis) is anadromous fish distributed in Yangtze River and East China Sea. In this study, we reported cleft-palate Chinese sturgeons in artificial population for the first time. In order to explore the genetic basis of palate malformation in A. sinensis, Illumina RNA-seq technology was used to analyze the transcriptome data of normal and cleft-palate individuals in farmed Chinese sturgeons. Raw reads were obtained and assembled into 808,612 unigenes, with an average length of 509.33 bp and an N50 of 574 bp. Sequence similarity analyses against four public databases (Nr, Uniprot, KEGG and COGs) found 158,642 unigenes that can be annotated. GABAergic synapse and TGF-β signal pathway were the most two enriched pathways with high Richfactor in the analyses of different expressed genes. In these two signal pathways, six genes (GABRA4, GS, GNS, S6K, PITX2, and BMP8) were found as cleft-palate genes in Chinese sturgeon. These findings contribute to our understanding of the genetic basis of cleft palate in sturgeon, while simultaneously adding to our knowledge about craniofacial development.
Project description:Chemical innovation is essential for fungi to adapt to ever-changing environments. However, the role of genetic and environmental interactions in driving fungal metabolic differentiation remains ambiguous. Here, we studied the phylogeographic diversity of a panel of 1,052 Aspergillus flavus strains across four continents, including 544 newly sequenced strains from China that revealed new global subpopulations. The population diversity of A. flavus shows strong phylogeographic metabolic patterns, with different clades being associated with specific environments.
2025-01-28 | MSV000096982 | MassIVE
Project description:sediment bacterial community in Yangtze River and Jialing River of Chongqing, China
