Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Introgression across narrow contact zones shapes the genomic landscape of phylogenetic variation in an African bird clade

PROVIDER: PRJNA1238086 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR32785100_1.fastq.gz	Fastqsanger.gz
	SRR32785100_2.fastq.gz	Fastqsanger.gz
	SRR32785200_1.fastq.gz	Fastqsanger.gz
	SRR32785200_2.fastq.gz	Fastqsanger.gz
	SRR32785101_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 292

Similar Datasets

Project description:Introgression across narrow contact zones shapes the genomic landscape of phylogenetic variation in an African bird clade

| PRJNA1241442 | ENA

Project description:Contrasting signatures of introgression in North American box turtle (Terrapene spp.) contact zones

| PRJNA563121 | ENA

Project description:Secondary contact zones of closely-related Erebia butterflies overlap with narrow phenotypic and parasitic clines

| PRJNA640280 | ENA

Enamel proteins reveal biological sex and intrataxon variability within Paranthropus robustus

Project description:The evolutionary relationships among extinct African hominin species are highly debated and largely unresolved, due in part to a lack of molecular data. Even within taxa, it is not always clear, based on morphology alone, whether ranges of variation are due to sexual dimorphism versus potentially undescribed taxonomic diversity. For Paranthropus robustus, a Pleistocene hominin found only in South Africa, both phylogenetic relationships to other taxa, and the nature of intraspecific variation are still debated. Here we report the first successful mass spectrometric sequencing of enamel proteomes from four ca. 2 million years old dental specimens morphologically identified as P. robustus from the site of Swartkrans.

2025-06-09 | PXD040221 | Pride

Genotyping by array of genomic variation in seven Khoe-San groups to reveal adaptation and complex African history

Project description:The history of click-speaking Khoe-San, and African populations in general, remains poorly understood. We genotyped ~2.3 million SNPs in 220 southern Africans and found that the Khoe-San diverged from other populations at least 100,000 years ago, but structure within the Khoe-San dated back to about 35,000 years ago. Genetic variation in various sub-Saharan populations did not localize the origin of modern humans to a single geographic region within Africa, instead, it indicated a history of admixture and stratification. We found evidence of adaptation targeting muscle function and immune response, potential adaptive introgression of UV-light protection, and selection predating modern human diversification involving skeletal and neurological development. These new findings illustrate the importance of African genomic diversity in understanding human evolutionary history .220 samples were analysed with the Illumina HumanOmni2.5-Quad BeadChip and are described herein.

2012-09-22 | E-MTAB-1259 | biostudies-arrayexpress

Zone of Inhibition Study with Tetromadurin Isolation

Project description:Isolation and dereplication of antitubercular compounds produced by South African fila-mentous actinobacteria by HPLC-MS/MS anal-ysis of their zones of growth inhibition

2023-02-27 | MSV000091368 | MassIVE

Transcription profiling by array of Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection

Project description:Streptococcus pneumoniae of serotype 3 possess a mucoid capsule and cause disease associated with high mortality rates relative to other pneumococci. Phylogenetic analysis of a complete reference genome and 81 draft sequences from clonal complex 180, the predominant serotype 3 clone in much of the world, found most sampled isolates belonged to a clade affected by few diversifying recombinations. However, other isolates indicate significant genetic variation has accumulated over the clonal complex's entire history. Two closely related genomes, one from the blood and another from the cerebrospinal fluid, were obtained from a patient with meningitis. The pair differed in their behaviour in a mouse model of disease and in their susceptibility to antimicrobials, with at least some of these changes attributable to a mutation that up-regulated the patAB efflux pump. This indicates clinically important phenotypic variation can accumulate rapidly through small alterations to the genotype. [Data is also available from http://bugs.sgul.ac.uk/E-BUGS-144]

2013-11-02 | E-BUGS-144 | biostudies-arrayexpress

The landscape of mouse meiotic double-strand break formation, processing and repair

Project description:SPO11 generates hundreds of DNA double-strand breaks (DSBs) to initiate meiotic recombination. Heritability and genome stability are shaped by the nonrandom distribution of DSBs, but mechanisms molding this landscape remain poorly understood. Here we exploit genome-wide maps of mouse DSBs at unprecedented nucleotide resolution to uncover previously invisible spatial features of recombination. At fine scale, we reveal a stereotyped hotspot structure––DSBs occur within narrow zones between methylated nucleosomes––and identify relationships between SPO11, chromatin, and the histone methyltransferase PRDM9. At large scale, DSB formation is suppressed on non-homologous portions of the sex chromosomes via the DSB-responsive kinase ATM, which also shapes the autosomal DSB landscape at multiple size scales. We also provide the first genome-wide analysis of exonucleolytic DSB resection lengths and elucidate spatial relationships between DSBs and recombination products. Our results paint a comprehensive picture of features that govern successive steps in mammalian meiotic recombination.

2016-08-13 | GSE84689 | GEO

Project description:Contact zones and species delimitation in Lampropeltis

| PRJNA884341 | ENA

Inter- and intra-lineage genetic diversity of wild-type Zika viruses reveals both common and distinctive nucleotide variants and clusters of genomic diversity

Project description:ZIKV strains belong to three phylogenetic lineages: East African, West African, and Asian/American. RNA virus genomes exist as populations of genetically-related sequences whose heterogeneity may impact viral fitness, evolution, and virulence. The genetic diversity of representative ZIKVs (N=7) from each lineage was examined using next generation sequencing (NGS) paired with downstream Shannon entropy calculation and single nucleotide variant (SNV) analysis. This comprehensive analysis of ZIKV genetic diversity provides insight into the genetic diversity of ZKIV and repository of SNV positions across lineages.

2019-07-30 | E-MTAB-7771 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data