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CD177+ neutrophils to restrict neuroinflammation following CNS injury

ABSTRACT: CD177+ neutrophils to restrict neuroinflammation following CNS injury

PROVIDER: PRJNA1242790 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR32895825_1.fastq.gz	Fastqsanger.gz
	SRR32895825_2.fastq.gz	Fastqsanger.gz
	SRR32895826_1.fastq.gz	Fastqsanger.gz
	SRR32895826_2.fastq.gz	Fastqsanger.gz

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CD177+ neutrophils restrict neuroinflammation following CNS injury

Project description:Neutrophils are the most abundant circulating leukocyte population that play critical roles in neuroinflammation after ischemic stroke. CD177, a glycoprotein on neutrophils, is emerging as an important immune regulator which fundamentally affects multiple inflammatory diseases. However, the role and regulatory mechanism of CD177 protein of neutrophils in neuroinflammation remains elusive. Using single-cell RNA sequencing (scRNA-Seq), we characterized CD177high neutrophils as a novel anti-inflammatory subset in response to ischemic stroke.

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Effect of isolated neutrophils from Cd177 knockout mice post-SCI on microglia in a co-culture system

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2024-09-10 | GSE276429 | GEO

Effect of isolated neutrophils from Cd177 knockout mice post-SCI on macrophages in a co-culture system

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Effect of isolated neutrophils from Cd177 knockout mice post-SCI on microglia in a co-culture system

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