Project description:We performed single-nucleus ATAC-seq (snATAC-seq) to profile chromatin accessibility across eight brain regions from C57BL/6J male and female mice at 2, 9, and 18 months of age. Nuclei were isolated from frozen dissected brain regions, tagmented using barcoded Tn5, and sequenced using combinatorial barcoding or 10x Multiome (female samples). Our analysis reveals region- and age-dependent chromatin changes, highlighting regulatory programs associated with aging in specific brain cell types.

2025-05-02 | GSE294772 | GEO

Single cell 10X Genomics Multiome Analysis of H3.3K4M Mutant Brain Samples

Project description:This SuperSeries is composed of the SubSeries listed below.

2025-07-14 | GSE293881 | GEO

10x Multiome from Human Fetal Heart

Project description:10x Multiome from Human Fetal Heart

| PRJNA1162163 | ENA

10x Multiome from Human Fetal Heart

Project description:10x Multiome from Human Fetal Heart

| PRJNA1162162 | ENA

Multiome experiment from GLI3 KO brain organoids

Project description:To study the effect of GLI3 knockout on early brain organoid development, we collected single-cell multiome data from 18 day old brain organoids

2022-08-25 | E-MTAB-12002 | biostudies-arrayexpress

10X sc-multiome data of NCIH2170 cell line

Project description:NCIH2170 is a lung cancer cell line harboring a large amount of extrachromosomal DNA (ecDNA) with high cell-to-cell variation. We performed 10X sc-multiome sequencing on this cell line to study the pattern of gene expression and chromatin accessibility with the existence of ecDNA.

2025-05-12 | GSE293273 | GEO

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