Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Transcriptome sequencing of restrictive diet mice

PROVIDER: PRJNA1260448 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR33473038_1.fastq.gz	Fastqsanger.gz
	SRR33473038_2.fastq.gz	Fastqsanger.gz
	SRR33473039_1.fastq.gz	Fastqsanger.gz
	SRR33473039_2.fastq.gz	Fastqsanger.gz
	SRR33473040_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Project description:16S sequencing of intestinal contents in restrictive diet mice

| PRJNA1259772 | ENA

RNA-sequencing comparison of murine cardiac endothelials from ketogenic and control diet mice

Project description:RNA-sequencing was used to compare the transcriptome in cardiac endothelial cells from mice fed a ketogenic diet or control diet.

2021-12-24 | GSE191173 | GEO

Comprehensive Analysis of the Translatome in High Fat Diet-Induced Liver Steatosis

Project description:We performed translatome and transcriptome sequencing (RNC-seq and RNA-seq) on the livers of normal chow diet-, high-fat diet- and High-fat diet plus lycopene-fed mice.

2020-03-10 | GSE146627 | GEO

Nobiletin ameliorates high fat-induced disruptions in rhythmic glucagon-like peptide-1 secretion - 16S

Project description:16S rRNA gene sequencing of colonic feces from mice fed regular chow, regular chow+nobiletin, high-fat diet or high-fat diet+nobiletin.

2022-05-06 | E-MTAB-11551 | biostudies-arrayexpress

Tension sensing by FAK governs nuclear mechanotransduction, trancriptome and fate endothelial transcriptome and fate

Project description:Endothelial cell (EC) attachment to the matrix and adjacent cells generates a mechanical environment that maintains a restrictive barrier against the uncontrolled influx of circulating protein and immune cells. Mechanisms that mediate the transition from restrictive to leaky endothelium, a hallmark of tissue injury exemplified by acute lung injury (ALI), remain elusive. Here, we show that FAK sensing and transmission of mechanical tension to the EC nucleus governs cell fate. In FAK-deleted EC, increased EC tension activated DNMT3a, which induced methylation of the KLF2 promoter leading to impaired synthesis of KLF2 and restrictive EC transcriptome, including S1PR1. FAK suppressed DNMT3a activity by restricting the tyrosine phosphorylation of nuclear envelope protein, emerin at Y74/Y95, and its localization in a nuclear cap. Inhibiting emerin phosphorylation or DNMT3a activity in damaged lungs enabled KLF2 transcription of S1PR1, rescuing the restrictive EC phenotype. Our works reveal a paradigm whereby FAK sensing of tension transmission to the nucleus maintains restrictive EC transcriptome and lung homeostasis.

2022-08-28 | GSE212037 | GEO

Transcriptome profiling of murine liver from EndoV knock-out and wildtype mice

Project description:We performed high-throughput RNA sequencing to characterize possible differences in the transcriptome of murine liver from both 12 months old EndoV and wildtype mice mice fed a regular diet.

2020-02-10 | GSE144779 | GEO

RNA-seq data for tumor tissues from mice fed with normal diet (ND) or high cholesterol diet (HCD)

Project description:To address how serum cholesterol affected tumor progression, C57BL/6J mice were placed on either normal diet or high cholesterol diet for 4 weeks, and then B16F10 cells were subcutaneously injected into the right flanks of mice. We performed transcriptome sequencing analysis (RNA-seq) on tumor tissues from ND and HCD groups.

2017-10-02 | GSE104463 | GEO

RNA-seq data for tumor tissues from mice fed with normal diet (ND) or high cholesterol diet (HCD) [Hep1-6]

Project description:To address how serum cholesterol affected tumor progression, C57BL/6J mice were placed on either normal diet or high cholesterol diet for 4 weeks, and then Hep1-6 cells were subcutaneously injected into the right flanks of mice. We performed transcriptome sequencing analysis (RNA-seq) on tumor tissues from ND and HCD groups.

2019-02-03 | GSE124599 | GEO

RNA-seq data for tumor tissues from mice fed with normal diet (ND) or high cholesterol diet (HCD) II

2021-05-25 | GSE114930 | GEO

Transcriptome and epigenome analysis of DIAMOND mice (ChIP-Seq)

Project description:The purpose of this experiment is to characterize changes in the transcriptome and epigenome in diet-associated liver cancer. For that we used the DIAMOND mice as a model organism and performed RNA-seq and H3K27Ac and H3K27Me3 ChIP-seq in livers from control mice (fed with a regular diet) and livers and tumours from western diet fed mice.

2024-10-23 | GSE220576 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data