Project description:To elucidate the mechanism by which Arctium lappa L. polysaccharide (ALP) promotes epidermal stem cell (EpSC) proliferation, we performed RNA sequencing on EpSCs from mice that were treated with either 30 μg/mL ALP or a vehicle control for 48 hours. This approach provided a comprehensive view of the ALP-regulated transcriptome profile.
Project description:Lappaol F, a natural lignin isolated from the seeds of Arctium lappa L., was previously shown to have an inhibitory effect on tumour cells and might be a promising drug candidate for cancer chemotherapy. In the present study, human colon cancer cell line SW480 was treated with Lappaol F, and quantitative proteomic analysis was performed to evaluate the effects of Lappaol F on protein expression in cancer cells.
