Project description:The polygenic nature of essential hypertension and its dependence on environmental factors pose a challenge for biomedical research. We hypothesized that microarray analysis of differential gene expression in peripheral blood cells would distinguish patients with hypertension from normotensive controls. We utilized microaaray analysis of differential gene expression in peripheral blood cells to identify differences in transcription profile of human essential hypertension compared with normotensive volunteers.
Project description:Microarray analysis of peripheral blood monocytes from patients with Alzheimer's disease or mild cognitive impairment and healthy individuals
Project description:The polygenic nature of essential hypertension and its dependence on environmental factors pose a challenge for biomedical research. We hypothesized that microarray analysis of differential gene expression in peripheral blood cells would distinguish patients with hypertension from normotensive controls. We utilized microaaray analysis of differential gene expression in peripheral blood cells to identify differences in transcription profile of human essential hypertension compared with normotensive volunteers. Samples were pooled from participants who met with our recruitment criteria for RNA extraction and hybridization on Affymetrix Gene Chips Human Genome U133 Plus 2.0 Array. Experiments were performed at CapitalBio Corporation (Beijing, China)
Project description:RNA seq experiment of Treg cells isolated from peripheral blood of patients with pulmonary sarcoidosis compared to Treg cells from peripheral blood of healthy individuals
Project description:Transcription profiling by array of human peripheral blood mononuclear cells from juvenile idiopathic arthritis patients before and after treatment with methotrexate