Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA143267 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:One of the central issues in evolutionary developmental biology is how we can formulate the relationships between evolutionary and developmental processes. Two major models have been proposed: the 'funnel-like' model, in which the earliest embryo shows the most conserved morphological pattern, followed by diversifying later stages, and the 'hourglass' model, in which constraints are imposed to conserve organogenesis stages, which is called the phylotypic period. Here we perform a quantitative comparative transcriptome analysis of several model vertebrate embryos and show that the pharyngula stage is most conserved, whereas earlier and later stages are rather divergent. These results allow us to predict approximate developmental timetables between different species, and indicate that pharyngula embryos have the most conserved gene expression profiles, which may be the source of the basic body plan of vertebrates. Refer to individual Series. This SuperSeries is composed of the following subset Series: GSE28388: [E-MTAB-366] Transcription profiling by array of chicken embryos at 15 different stages GSE28389: [E-MTAB-368] Transcription profiling by array of mouse embryos at 8 different stages GSE28390: [E-MTAB-369] Transcription profiling by array of Xenopus laevis embryos at 15 different stages Refer to individual Series
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| PRJNA143263 | ENA
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