Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Caenorhabditis elegans

ABSTRACT: The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.

PROVIDER: PRJNA147691 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR346783.fastq.gz	Fastqsanger.gz
	SRR346784.fastq.gz	Fastqsanger.gz
	SRR346785.fastq.gz	Fastqsanger.gz
	SRR346786.fastq.gz	Fastqsanger.gz
	SRR346787.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 7

Similar Datasets

Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons

Project description:To examine the roles of the ADAR genes and the ERI-6/7 helicase in endogenous RNAi pathways, we sequenced small RNA of adr-1; adr-2; eri-6 mutants. We also analyzed the transcriptomes of these mutants using total RNAseq and mRNAseq. mRNAseq was done in mutants depleted for the RNAi factors drh-1 and nrde-3, or control RNAi

2020-01-14 | GSE143595 | GEO

The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.

Project description:To characterize the role of the ERI-6/7 helicase in endogenous small RNA pathways in C. elegans, small RNA populations from null alleles of eri-6 and eri-7, and from mutants of known endogenous RNAi pathway factors, eri-1 and ergo-1, were determined by deep sequencing, and compared to wild type. Small RNA analysis in wild type and eri-1, ergo-1, eri-6 and eri-7 mutant C. elegans strains.

2011-09-25 | E-GEOD-32366 | biostudies-arrayexpress

The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.

2011-09-25 | GSE32366 | GEO

Caenorhabditis elegans

Project description:Analysis of 22G siRNA triggered siRNA amplification in Caenorhabditis elegans

| PRJNA156415 | ENA

Whole genome microarray analysis of C. elegans rrf-3 and eri-1 mutants

Project description:RRF-3 and ERI-1 are first identified proteins required for accumulation of at least some endogenous secondary siRNAs in C.elegans. Genome wide gene expression analysis was performed on L4 stage rrf-3 and eri-1 mutant C. elegans to study effects caused by loss of these proteins. Mutant rrf-3 and eri-1 strains exhibited similar expression patterns when compared to N2 wild type, while 72 transcripts were found to be co-overexpressed and 4 transcripts co-underexpressed (> 2-fold, p< 0.05). Ontology analysis indicated many of the gene products were associated with protein phosphorylation and sperm function. These results provide additional support for the hypothesis that RRF-3 and ERI-1 act together in a siRNA pathway and may indicate biological processes that are related to endo-siRNAs. Keywords: Mutant vs. wild type -comparison

2007-10-19 | GSE8659 | GEO

Caenorhabditis elegans

Project description:A Ribonuclease Coordinates siRNA Amplification and mRNA Cleavage during RNAi

| PRJNA255110 | ENA

Analysis of 22G siRNA triggered siRNA amplification in Caenorhabditis elegans

Project description:To determine if an endogenous 22G siRNA sensor transgene is subject to siRNA amplification, small RNAs were deep sequenced from the sensor and from a control transgene that is identical to the sensor but lacks an siRNA target site.

2011-12-10 | GSE34320 | GEO

Analysis of transgene siRNAs and ARL-8-dependent siRNAs in Caenorhabditis elegans

Project description:We analyzed the C. elegans small RNA response to high copy transgene sequences expressed in the soma in a wild type and an eri-6/7 mutant background. We also analyzed small RNA defects in the arl-8(tm2472) mutant. Transgene siRNAs are 22 nt long, mostly antisense, and correspond to the promoter, coding regions, the 3'UTR and plamsid sequences present on the transgene. Transgene siRNAs are decreased in the eri-6/7 mutant. In the arl-8 mutant, 26G siRNAs in the ALG-3/4 dependent endogenous RNAi pathway are decreased.

2013-12-15 | GSE52785 | GEO

Caenorhabditis elegans

Project description:The DEAD box helicase RDE-12 promotes amplification of RNAi in cytoplasmic foci in C. elegans

| PRJNA233484 | ENA

Caenorhabditis elegans

Project description:The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification

| PRJNA158125 | ENA