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Mycobacterium avium subsp. paratuberculosis

ABSTRACT: Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line

PROVIDER: PRJNA154883 | ENA |

REPOSITORIES: ENA

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Mycobacterium avium subsp. paratuberculosis gene transcription in simulated phagosomal environment and in human macrophage infection

Project description:This SuperSeries is composed of the following subset Series: GSE32241: Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro acid-nitrosative multi-stress GSE32242: Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line Refer to individual Series

2012-05-31 | E-GEOD-32243 | biostudies-arrayexpress

Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line

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Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro acid-nitrosative multi-stress

Project description:Transcriptional profile of Mycobacterium avium subspecies paratuberculosis in in vitro acid-nitrosative multistress, comparing untreated control cells and bacteria under multi-stress.

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Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line

Project description:Transcriptional profile of Mycobacterium avium subspecies paratuberculosis in in vitro THP-1 (ATCC TIB-202) cell line infection, comparing bacteria grown in host medium and intracellular bacteria recovered from infected THP-1 cells. Two-condition experiment, MAP-K vs. intracellular MAP-THP-1. Biological replicates: 10 controls, 10 intracellular MAP-THP-1, independently grown and harvested. In controls and intracellular MAP-THP-1 cells, good quality RNA samples obtained from each pellet were pooled together and used for microarray experiments to get an average of 10 separate experiments, four replicates per array.

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Mycobacterium avium subsp. paratuberculosis

Project description:Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro acid-nitrosative multi-stress

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Project description:Differentially regulated genes induced by in vitro generated Mycobacterium avium subspecies paratuberculosis cell wall deficient forms

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Analysis of long non-coding RNA and mRNA expression in bovine macrophages brings up novel aspects of Mycobacterium avium subspecies paratuberculosis infections

Project description:The alteration in genomic expression profiles of mRNA and long non-coding RNA (lncRNA) in bovine macrophages in response to Mycobacterium avium subspecies paratuberculosis (MAP) infection was investigated by applying an RNA-Seq based approach. A computational pipeline was implemented which identified more than 300 unannotated lncRNAs in macrophages of which 38 were differentially regulated by the infection.

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