Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA171115 | ENA |
REPOSITORIES: ENA
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Project description:The adaptor protein Lnk is an important negative regulator of HSC homeostasis and self-renewal. This study aims to investigate the role of Lnk in HSC aging. Here we performed expression profiling of bone marrow CD150+CD48-LSK LT-HSCs from young and old WT and Lnk-/- mice. Results identify select Lnk-mediated pathways with potential involvement in HSC self-renewal and aging.
2012-10-03 | GSE39553 | GEO
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