Project description:Biological ingredient analysis of traditional Chinese medicine preparation based on high-throughput sequencing: more stories on a variety of TCM preparations
Project description:Potentilla indica and Melastoma dodecandrum lour are medicinal herbs used in traditional Chinese medicine. We sampled the plants from Nanyang Technological University's herb garden for transcriptomics analysis.
Project description:To identify biomarkers regulated by traditional Chinese medicine Astragalus membranaceus Fischer Bge. var. mongolicus Bge. Hsiao in colorectal cancer. We have identified several differentially expressed genes including microRNAs using Affymetrix HTA-2.0 array. In this dataset, we include the expression data obtained from colon cancer cell line HCT116 grafted into nude mice. The mice was treated either water or traditional Chinese medicine Astragalus membranaceus for 28 days. These data are used to obtain 1425 genes that are differentially expressed in response to Astragalus membranaceus treatment.
2017-02-13 | GSE70772 | GEO
Project description:Traditional Chinese Medicine Public Health Special Project
| PRJNA665927 | ENA
Project description:Traditional Chinese Medicine Public Health Special Project
Project description:This study, based on RNA-seq technology, systematically compared the transcriptomic differences between the normal control group, LPS model group, and LPS + Traditional Chinese Medicine extract treatment group. The aim was to screen key differential genes (DEGs) and their enriched core pathways under drug intervention. The results showed that the active extract of Traditional Chinese Medicine significantly reshaped the gene expression profile in RAW264.7 cells related to biological processes such as metabolic reprogramming, ferroptosis, inflammation response, and immune regulation, suggesting its potential for multi-target and multi-pathway immune-metabolic regulation.