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Mus musculus

ABSTRACT: Genome-wide profiling of muscle Treg cells from IL-33 treated mice

PROVIDER: PRJNA308481 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR3096870_1.fastq.gz	Fastqsanger.gz
	SRR3096870_2.fastq.gz	Fastqsanger.gz
	SRR3096869_1.fastq.gz	Fastqsanger.gz
	SRR3096869_2.fastq.gz	Fastqsanger.gz

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Genome-wide profiling of muscle Treg cells from IL-33 treated mice

Project description:We report gene expression of Treg cells isolated from injured muscle in IL-33 vs PBS treated mice. Male Foxp3-GFP C57BL/6 reporter (2 months old) mice were injured intramuscularly with cardiotoxin/rIL-33 (0.3 ug/muscle). Tregs were sorted directly into Trizol from injured muscle 4 days post-injury. Gene expression profiling of muscle Tregs from IL-33 vs PBS injured mice.

2016-01-12 | E-GEOD-76722 | biostudies-arrayexpress

Genome-wide profiling of muscle Treg cells from IL-33 treated mice

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Project description:We investigated the transcriptional profiles of lung ILC2, Th2 and Treg (Gata3+ and -) cells from naïve and IL-33-treated mice. This experiment accompanies our manuscript, where we showed that IL-33-dependent accumulation of adaptive type-2 immune cells (Th2 and Treg) was dependent on OX40L expression by ILC2.

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