Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Sociality and DNA methylation are not evolutionary dependent

ABSTRACT: Sociality and DNA methylation are not evolutionary dependent

PROVIDER: PRJNA326247 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR3702940.fastq.gz	Fastqsanger.gz
	SRR3702950.fastq.gz	Fastqsanger.gz
	SRR3702960.fastq.gz	Fastqsanger.gz
	SRR3702970.fastq.gz	Fastqsanger.gz
	SRR3702980.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 69

Similar Datasets

Sociality and DNA methylation are not evolutionary dependent

Project description:DNA methylation is an important chromatin modification that is necessary for the structural integrity and proper regulation of the genome for many species. Despite its conservation across the tree of life, little is known about its contribution to complex traits. Reports that differences in DNA methylation between castes in closely related Hymenopteran insects (ants, bees and wasps) contributes to social behaviors has generated hypotheses on the role of DNA methylation in governing social behavior. However, social behavior has evolved multiple times across insecta, and a common role of DNA methylation in social behavior remains outstanding. Using phylogenetic comparative methods we sought to better understand patterns of DNA methylation and social behavior across insects. DNA methylation can be found in social and solitary insects from all orders, except Diptera (flies), which suggests a shared loss of DNA methylation within this order. The lack of DNA methylation is reflected in the absence of the maintenance and de novo DNA methyltransferases (DNMT) 1 and 3, respectively. Interestingly, DNA methylation is found in species without DNMT3. DNA methylation and social behavior (social/solitary) or with division of labor (caste+/caste–) for 123 insect species analyzed from 11 orders are not evolutionary dependent, which is further supported by sequencing of DNA methylomes from 40 species.

2017-02-02 | GSE83497 | GEO

CpG context and content in evolutionary signatures of brain DNA methylation

Project description:We assayed CpG methylation in cerebral cortex of neurologically and psychiatrically normal human postmortem specimens, as well as mouse forebrain specimens. Cross-species human-mouse DNA methylation conservation analysis shows that DNA methylation is not correlated with sequence conservation. Instead, greater DNA methylation conservation is correlated with increasing CpG density. We identified key genomic features that can be targeted for identification of epigenetic loci that may be developmentally and evolutionarily conserved and wherein aberrations in DNA methylation patterns can confer risk for disease. Characterization of evolutionary signatures of DNA methylation in the brain

2011-10-04 | E-GEOD-32647 | biostudies-arrayexpress

Evolutionary Significance of DNA Methylation in Human and Chimpanzee Brains

Project description:We compared the genome-wide patterns of DNA methylation in the brains of humans to those of our closest evolutionary relative, chimpanzees, using base-pair resolution whole-genome methylation maps of the prefrontal cortex. Our data reveal that the prefrontal cortex is the most heavily methylated among the human tissues examined so far. Nevertheless, hundreds of genes exhibit dramatically reduced levels of promoter DNA methylation in the human brain relative to the chimpanzee brain. Many of these genes are associated with neurological disorders, psychological disorders, and cancers, and are enriched for functions related to cellular metabolic processes and protein binding. Moreover, the majority of these genes exhibit higher expression in the human brain compared to the chimpanzee brain. Profiling DNA methylation map in prefrontal cortex regions of postmortem brains of three humans and three chimpanzees

2012-09-04 | E-GEOD-37202 | biostudies-arrayexpress

Genome-wide evolutionary analysis of eukaryotic DNA methylation

Project description:Genome-wide evolutionary analysis of eukaryotic DNA methylation

| PRJNA122153 | ENA

RNautophagic regulation of DNMT3a-dependent DNA methylation

Project description:RNautophagic regulation of DNMT3a-dependent DNA methylation

| PRJNA874430 | ENA

RNautophagic regulation of DNMT3a-dependent DNA methylation

Project description:RNautophagic regulation of DNMT3a-dependent DNA methylation

| PRJNA866390 | ENA

Evolutionary Significance of DNA Methylation in Human and Chimpanzee Brains

Project description:Evolutionary Significance of DNA Methylation in Human and Chimpanzee Brains

| PRJNA158561 | ENA

Context-dependent DNA methylation signatures in animal livestock

Project description:Context-dependent DNA methylation signatures in animal livestock

| PRJNA865267 | ENA

Age-dependent DNA methylation characterization of the rat supraoptic nucleus (Methylation)

Project description:Age-dependent DNA methylation characterization of the rat supraoptic nucleus (Methylation)

| PRJNA967023 | ENA

Evolutionary Significance of DNA Methylation in Human and Chimpanzee Brains

2012-09-04 | GSE37202 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data