Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: H4K16ac modification profile difference between Peg3-WT and KO MEF cells

PROVIDER: PRJNA381884 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5421610.fastq.gz	Fastqsanger.gz
	SRR5421611.fastq.gz	Fastqsanger.gz
	SRR5421612.fastq.gz	Fastqsanger.gz
	SRR5421613.fastq.gz	Fastqsanger.gz
	SRR5421614.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

H4K16ac modification profile difference between Peg3-WT and KO MEF cells

Project description:PEG3 (Paternally Expressed Gene 3) is an imprinted gene encoding a DNA-binding protein. Two components of the mammalian MSL (Male-Specific Lethal) complex, Msl1 and Msl3, are known to be the genomic targets of PEG3. In this report, we performed genome-wide ChIP-seq experiments profiling H4K16ac levels using a set of MEF cells (Mouse Embryonic Fibroblast), the WT and KO of Peg3. The results indicated that about 10% of the mouse gene catalog showed high levels of H4K16ac levels in Peg3-KO MEFs than in Peg3-WT MEFs. This further suggests that mammalian Peg3 may control its downstream genes through the MSL complex.

2017-08-15 | GSE97459 | GEO

Global examination of H3K9me3 levels and PEG3 binding sites between WT and KO

Project description:PEG3 (Paternally Expressed Gene 3) is an imprinted gene encoding a DNA-binding protein. In this study, we used MEF cells (Mouse Embryonic Fibroblast). We performed genome-wide ChIP-seq experiments profiling H3K9me3 levels as well as examine the set of genomic targets and also redefines the DNA-binding motif for the imprinted transcription factor, PEG3 in the WT and KO of Peg3. The results suggested high levels of H3K9 levels in Peg3-KO MEFs than in Peg3-WT MEFs, whereas several different genes involved several biochemical pathways seems to be have potential binding site for PEG3 protein, which tend to have a distinct profile of binding motif to its binding region. This further suggests that mammalian Peg3 may control its downstream genes in regulating several biological functions and regulate the H3K9 methylation levels.

2021-07-31 | GSE181069 | GEO

Project description:difference between WT and ko mouse

| PRJNA691984 | ENA

Profiling Mouse embryonic fibroblasts from wt and SARAF KO animals

Project description:comparing SARAF KO transcription profile in MEF, comparing to cell from wt animals

2022-01-13 | GSE193354 | GEO

Mus musculus

Project description:MEF wt versus Med23-/- KO after 20% Serum Stimulation

| PRJNA115639 | ENA

Global examination of H3K9me3 levels and PEG3 binding sites between WT and KO

Project description:Global examination of H3K9me3 levels and PEG3 binding sites between WT and KO

| PRJNA750512 | ENA

Impact of Peg3 deletion in mouse trophoblast stem cells on H3K9me3 profiles

Project description:Peg3 is an imprinted gene that in itself is a KRAB zinc finger protein. We established knockout trophoblast stem cell lines (TSCs) in which we ablated the majority of the zinc finger motifs of the PEG3 coding region using CRISPR-Cas9-mediated deletion. We then profiled wild-type (WT) and knockout (KO) TSC lines for the genome-wide distribution of the epigenetic repressive mark H3K9me3 by ChIP-seq.

2026-06-19 | GSE331039 | GEO

National University of Singapore MEF

Project description:miRNA expression of 6h EBSS treatment induced autophagy in Atg5 WT and KO mouse embryonic fibroblasts (MEF) were examined. For the 1st comparison, the control group is Atg5 WT MEF without EBSS treatment, the experiment group is Atg5 KO MEF without EBSS treatment; For the 2nd comparison, the control group is Atg5 WT MEF without EBSS treatment, the experiment group is Atg5 WT MEF with 6h EBSS treatment; For the 3rd comparison, the control group is Atg5 WT MEF with 6h EBSS treatment, the experiment group is Atg5 KO MEF with 6h EBSS treatment.The PIQORTM Analyzer were used for the analysis.

2011-11-21 | E-MTAB-880 | biostudies-arrayexpress

Identification of targets regulated by MLL1 in response to HSP90 inhibitors

Project description:MLL1 WT or KO MEF with and without HSP90 inhibitor treatment

2014-04-15 | GSE56492 | GEO

Effects of O-GlcNAc modification on gene expression using O-GlcNAcase deleted Mouse Embryonic Fibroblast cells.

Project description:Single O-GlcNAc modification orchestrate by O-GlcNAc Transferase (OGT) and O-GlcNAcase (OGA alias MGEA5) enzymes, affects signal transduction and gene expression by chromatin modulation. We developed Oga deleted MEF (mouse embryonic fibroblast) cells to investigate effects of O-GlcNAc modification in mice. RNA isolated from Mouse Embryonic Fibroblast cells generated from Oga Knock out (KO) Heterozygous (Het) and wild type (WT) cells and subjected to microarray analysis. Results provide insight into regulatory pattern of O-GlcNAc modification, and associated signaling pathways

2014-12-29 | GSE52721 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data