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Methionine supplementation and radiation in mouse jejunum

ABSTRACT: Methionine supplementation and radiation in mouse jejunum

PROVIDER: PRJNA437410 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6818690.fastq.gz	Fastqsanger.gz
	SRR6818700.fastq.gz	Fastqsanger.gz
	SRR6818691.fastq.gz	Fastqsanger.gz
	SRR6818701.fastq.gz	Fastqsanger.gz
	SRR6818692.fastq.gz	Fastqsanger.gz

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Methionine supplementation and radiation in mouse jejunum

Project description:Methionine supplementation exarcerbates radiation injury in the mouse jejunum

2018-03-09 | GSE111558 | GEO

RNA sequence for mammary gland of ICR mice at pregnant day 17 with supplementation of methionine (Met) alone or with methionyl-methionine (Met-Met) dipeptide.

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2025-10-21 | PXD068409 | Pride

Single cell RNA sequencing of post-radiation mouse jejunum with or without DIZE

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Effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos

Project description:Maternal nutrition exclusively during the periconceptional period can induce remarkable effects on both oocyte maturation and early embryo development, which in turn can have lifelong consequences. The objective of this study was to evaluate the effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos. Holstein cows were randomly assigned to one of two treatments differing in level of dietary methionine (1.89 Met vs. 2.43 Met % of metabolizable protein) from calving until embryo flushing. High quality preimplantation embryos from individual cows were pooled and then analyzed by RNA sequencing. A total of eight Holstein dairy cows were used in this study. Preimplantation embryos recovered from each cow were pooled in order to generate two replicates per cow assayed. Each pool consisted of 2-4 expanded blastocysts with excellent quality. Overall, a total of 16 embryo pools underwent RNA extraction, amplification, and subsequent sequencing.

2013-06-21 | E-GEOD-48147 | biostudies-arrayexpress

Effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos

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Maternal methionine supplementation alters the epigenome of the offspring

Project description:Maternal methionine supplementation alters the epigenome of the offspring

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Maternal methionine supplementation alters the epigenome of the offspring [RNA-Seq]

Project description:Maternal methionine supplementation alters the epigenome of the offspring [RNA-Seq]

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Maternal methionine supplementation alters the epigenome of the offspring [Bisulfite-Seq]

Project description:Maternal methionine supplementation alters the epigenome of the offspring [Bisulfite-Seq]

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Single cell RNA sequencing of post-radiation mouse jejunum with or without DIZE

Project description:In a radiation mass casualty event, exposed populations will suffer dose-dependent toxicity to multiple-organ systems. Although several therapies are FDA-approved for treatment of the hematopoietic acute radiation syndrome (H-ARS), there are no FDA-approved medical countermeasures (MCM) for either acute gastrointestinal injury (GI) or late multi-organ toxicities known as the delayed effects of acute radiation exposure (DEARE). Prior data suggest activation of the alternative renin angiotensin (RAS) enzyme angiotensin-converting enzyme 2 (ACE2) has therapeutic potential for mitigating multi-organ radiation injury, including GI acute radiation syndrome (GI-ARS). Here, we evaluated whether pharmacologic activation of ACE2 mitigates GI-ARS in rodent models and protects against DEARE in GI-ARS survivors.

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