Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Toxoplasma gondii infection of human retinal pigment epithelial cells

ABSTRACT: Toxoplasma gondii infection of human retinal pigment epithelial cells

PROVIDER: PRJNA545905 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR9180600_1.fastq.gz	Fastqsanger.gz
	SRR9180600_2.fastq.gz	Fastqsanger.gz
	SRR9180610_1.fastq.gz	Fastqsanger.gz
	SRR9180610_2.fastq.gz	Fastqsanger.gz
	SRR9180620.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 96

Similar Datasets

Toxoplasma gondii infection of human retinal pigment epithelial cells

Project description:We performed RNA-Sequencing (RNA-Seq) of primary human retinal pigment epithelial cells and the ARPE-19 cell line 24 hours following infection with GT-1 strain T. gondii tachyzoites. Gene ontology and pathway enrichment analyses of differentially expressed total RNA identified a strong immunologic transcriptomic signature. There were limited changes in the small RNA transcriptome. We used RT-qPCR for 26 immune response-related protein-coding and long non-coding transcripts in different primary epithelial cell isolates to confirm immunological activity of infected cells.

2019-06-04 | GSE132091 | GEO

Human retinal Mueller glial cell (HMG) response to Toxoplasma gondii infection

Project description:This experiment sough to understand the impact Toxoplasma gondii infection on the host transcriptome. We do this by sequencing both Total and Small RNA from 6 donors. Infection results is singificant alterations to both gene expression and miRNA experession. The GT1 strain of T. gondii induces different changes to that of GHPT strain.

2025-10-23 | GSE145836 | GEO

Toxoplasma gondii

Project description:Toxoplasma gondii

| PRJDA33425 | ENA

Genome-wide analysis of gene expression response upon infection with Toxoplasma gondii

Project description:The in vitro effect of infection with different strains of Toxoplasma gondii was tested 24 hours after infection of Human Foreskin Fibroblasts (HFF) The strains tested include RH, VEG, and transgenic strains of RH overexpressing ROP38 or ROP21 Total RNA of Toxoplasma gondii infected HFF cell was compared to uninfected cells

2010-07-31 | E-GEOD-22402 | biostudies-arrayexpress

Genome-wide gene expression analysis of WERI-Rb-1 (retinal cells) infected with Toxoplasma gondii over time

Project description:Analysis of gene expression patterms following infection of the parasite Toxoplasma gondii in a clinically relevant retinal cell line over a time course of 2 hours, 6 hours and 24 hours. Parasites were washed off after 2 hours to ensure that gene expression changes are truly reflective of an on-going infection, and not on-going parasite invasion.

2016-05-03 | GSE81016 | GEO

Genome-wide DNA methylation analysis of WERI-Rb-1 (retinal cells) infected with Toxoplasma gondii over time

Project description:Analysis of DNA methylation patterns following infection of the parasite Toxoplasma gondii in a clinically relevant retinal cell line over a time course of 2 hours, 6 hours and 24 hours. Parasites were washed off after 2 hours to ensure that methylation changes are truly reflective of an on-going infection, and not on-going parasite invasion.

2016-05-03 | GSE81015 | GEO

Toxoplasma gondii RNASeq

Project description:Recent advances in high throughput sequencing methodologies allow the opportunity to probe in depth the transcriptomes of organisms including N. caninum and Toxoplasma gondii. In this project, we are using Illumina sequencing technology to analyze the transcriptome (RNA-Seq) of experimentally accessible stages (e.g. tachyzoites at different times points) of T. gondii VEG strain. The aim is to make comparative transcriptional landscape maps of Neospora and Toxoplasma at different time points at different life cycle stages and compare levels of expression of orthologous genes in these two organisms.

2011-02-08 | E-MTAB-550 | biostudies-arrayexpress

Human retinal Mueller glial cell (HMG) response to Toxoplasma gondii infection

Project description:Human retinal Mueller glial cell (HMG) response to Toxoplasma gondii infection

| PRJNA608488 | ENA

Expression QTL mapping of Toxoplasma gondii genes

Project description:This SuperSeries is composed of the following subset Series: GSE11437: Expression QTL mapping of Toxoplasma gondii genes, Bradyzoite array GSE11514: Expression QTL mapping of Toxoplasma gondii genes, Tachyzoite array Keywords: SuperSeries Refer to individual Series

2008-05-22 | E-GEOD-11515 | biostudies-arrayexpress

Toxoplasma gondii

Project description:Toxoplasma gondii Genome sequencing

| PRJNA258152 | ENA