Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single cell transcriptome sequencing of gastric cancer cell lines

ABSTRACT: Single cell transcriptome sequencing of gastric cancer cell lines

PROVIDER: PRJNA598203 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10805145_1.fastq.gz	Fastqsanger.gz
	SRR10805145_2.fastq.gz	Fastqsanger.gz
	SRR10805146_1.fastq.gz	Fastqsanger.gz
	SRR10805146_2.fastq.gz	Fastqsanger.gz
	SRR10805147_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 22

Similar Datasets

Single cell transcriptome sequencing of gastric cancer cell lines

Project description:We report the integrative analysis of single cell genome and transcriptome characteristics of gastric cancer cell lines

2019-12-31 | GSE142750 | GEO

Single cell sequencing of mouse gastric cell populations

Project description:Single cell sequencing of mouse gastric cell populations

| PRJNA899113 | ENA

Transcriptome of EBV-infected gastric cancer cell lines

Project description:To understand epigenic dysregulation of host and viral genes upon EBV infection in human gastric cancer, genome wide transcripts by RNAseq were undertaken for total RNAs of 3 EBVnGC, their isogenic cell lines converted by in vitro EBV-infection and 3 EBV-naturally infected GC cell lines.

2014-09-01 | GSE60873 | GEO

Gastric Cancer Cell Lines

Project description:Regions of recurrent genomic amplification and deletion are frequently observed in primary gastric cancers (GC). However, identifying specific oncogenes and tumor suppressor genes within these regions can be challenging, as they often cover tens to hundreds of genes. Here, we combined high-resolution array-based comparative genomic hybridization (aCGH) with gene expression profiling to target genes lying within focal high-level amplifications in GC cell lines, and identified RAB23 as an amplified and overexpressed Chr 6p11p12 gene in Hs746T cells. High RAB23 protein expression was also observed in some lines lacking RAB23 amplification, suggesting additional mechanisms besides gene amplification for up-regulating RAB23. siRNA silencing of RAB23 reduced the invasive potential of both amplified and nonamplified GC cell lines. RAB23 gene amplifications were observed in 13% of primary gastric carcinomas. In two independent patient cohorts, RAB23 transcript and protein expression was significantly associated with diffuse-type gastric cancer (dGC) compared to intestinal-type gastric cancer (iGC), providing further evidence that dGC and iGC likely represent two molecularly distinct tumor types. Our study demonstrates that investigating focal chromosomal amplifications by combining highresolution aCGH with expression profiling is a powerful general strategy for identifying novel cancer genes in recurrent regions of chromosomal aberration. Keywords: gastric cancer cell lines, comparative genomic hybridization, gene expression profiling

2008-12-29 | GSE10611 | GEO

Gastric Cancer Cell Lines

2010-05-14 | E-GEOD-10611 | biostudies-arrayexpress

Single cell RNA sequencing of advanced gastric cancer

Project description:Single cell RNA sequencing of advanced gastric cancer

| PRJNA588620 | ENA

Epigenetic analysis of gastric cancer cell lines

2012-05-03 | GSE29499 | GEO

Targeted single cell RNA sequencing of T cells infiltrated in mouse gastric cancer.

Project description:YTN2 and YTN16 cells are chemically induced gastric cancer cell lines. YTN2 is spontaneously regressed in C57BL/6 mice in CD8+ T cell-dependent manner, while YTN16 grows progressively. To investigate tumor infiltrating T cells, we performed single-cell RNA-Seq of CD4+ and CD8+ T cells in YTN2 and YTN16 gastric tumor-bearing mice for 44 T cell-related genes (Supplementary Table 1).

2020-10-28 | GSE152888 | GEO

Gastric organoid single-cell RNA-seq

Project description:Gastric organoid single-cell RNA-seq

| PRJNA499101 | ENA

Epigenetic analysis of gastric cancer cell lines

Project description:Genome wide DNA methylation profiling of gastric cancer cell lines. The Illumina Goldengate DNA methylation Beadchip was used to obtain DNA methylation profiles across 1,505 CpG CpGs in 20 gastric cancer cell lines. Bisulphite converted DNA from the 20 gastric cancer cell lines were hybridised to the Illumina Goldengate Methylation Beadchip

2012-05-02 | E-GEOD-29499 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data