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Cap analysis gene analysis (CAGE) of Ba/F3 cells harbouring FLT3-ITD mutations (mouse)

ABSTRACT: Cap analysis gene analysis (CAGE) of Ba/F3 cells harbouring FLT3-ITD mutations (mouse)

PROVIDER: PRJNA630704 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11712284.fastq.gz	Fastqsanger.gz
	SRR11712285.fastq.gz	Fastqsanger.gz
	SRR11712286.fastq.gz	Fastqsanger.gz
	SRR11712287.fastq.gz	Fastqsanger.gz
	SRR11712288.fastq.gz	Fastqsanger.gz

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Cap analysis gene analysis (CAGE) of Ba/F3 cells harbouring FLT3-ITD mutations (mouse)

Project description:The purpose of the experiment is to investigate transcriptome signatures of FLT3-ITD and TKD double mutations in AML and the underlying molecular mechanism of mutation-driven acquired resistance. We identify 1945 upregulated and 1470 downregulated promoters in FLT3-ITD/D835 mutant Ba/F4 cells compared to cells with FLT3-ITD (FDR<0.05).

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Cap analysis gene analysis (CAGE) of AML cells harbouring FLT3-ITD mutations

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