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RNA-seq of ATF-3 overexpressing and Neomycin control melanoma cell lines

ABSTRACT: RNA-seq of ATF-3 overexpressing and Neomycin control melanoma cell lines

PROVIDER: PRJNA639461 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12014767.fastq.gz	Fastqsanger.gz
	SRR12014768.fastq.gz	Fastqsanger.gz
	SRR12014769.fastq.gz	Fastqsanger.gz
	SRR12014770.fastq.gz	Fastqsanger.gz
	SRR12014771.fastq.gz	Fastqsanger.gz

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RNA-seq of ATF-3 overexpressing and Neomycin control melanoma cell lines

Project description:The present study demonstrates that ATF-3 plays a tumor suppressing function in melanoma. Overexpression of ATF-3 in metastatic melanoma cell lines significantly inhibited their growth, migration and invasion in vitro as well as inhibited tumor growth in human melanoma xenograft mouse model in vivo.

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