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Intrauterine growth restriction causes abnormal embyronic dentate gyrus neurogenesis in mouse offspring that leads to adult learning and memory deficits

ABSTRACT: Intrauterine growth restriction causes abnormal embyronic dentate gyrus neurogenesis in mouse offspring that leads to adult learning and memory deficits

PROVIDER: PRJNA727306 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR14421291.fastq.gz	Fastqsanger.gz
	SRR14421292.fastq.gz	Fastqsanger.gz
	SRR14421293.fastq.gz	Fastqsanger.gz
	SRR14421294.fastq.gz	Fastqsanger.gz
	SRR14421295.fastq.gz	Fastqsanger.gz

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Intrauterine growth restriction causes abnormal embyronic dentate gyrus neurogenesis in mouse offspring that leads to adult learning and memory deficits

Project description:In our mouse model of intrauterine growth restriction (IUGR), we have discovered that IUGR promotes embyronic Sox2+ neural stem cell depletion as well as premature neurogenesis. Using RNA-seq, we strived to determine the differentially expressed molecular genes/pathways that may be responsible for such cellular differences between appropriately-grown and IUGR mouse offspring.

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