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ABSTRACT: Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis

PROVIDER: PRJNA900189 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR22254239_1.fastq.gz	Fastqsanger.gz
	SRR22254239_2.fastq.gz	Fastqsanger.gz
	SRR22254240_1.fastq.gz	Fastqsanger.gz
	SRR22254240_2.fastq.gz	Fastqsanger.gz

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Project description:Transcriptional profiling of human synovial tissue from thirteen individuals with arthralgia who were IgM rheumatoid factor (RF) and/or anti-citrullinated protein antibody (ACPA) positive and without any evidence of arthritis. Survival analysis was used to identify transcripts associated with arthritis after follow up. This study was performed to investigate the molecular changes in synovium preceding arthritis development in at risk individuals.

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