Project description:We performed microarray transcriptional profiling of rat prefrontal cortex 2 hours after the beginnig of acute inescapable footshock (FS) stress Samples were collected from rats exposed to FS stress and sacrificed 2 hours after the beginnig of 40-minutes stress section and from controls left undisturbed in their cage
Project description:We performed microarray transcriptional profiling of rat prefrontal cortex 24 hours after the beginnig of acute inescapable footshock (FS) stress Samples were collected from rats exposed to FS stress and sacrificed 24 hours after the beginnig of 40-minutes stress section and from controls left undisturbed in their cage
Project description:We performed microarray transcriptional profiling of rat prefrontal cortex after acute inescapable footshock (FS) stress Samples were collected from rats exposed to FS stress and sacrificed immediately after the 40-minutes stress section and from controls left undisturbed in their cage
Project description:This study investigates the molecular mechanisms of action of clozapine and risperidone in the rat brain, specifically targeting the prefrontal cortex (PFC) and the remaining cortical regions (CX). A multi-platform proteomic approach was employed to capture comprehensive changes in protein expression induced by chronic (21 days) antipsychotic drug treatment.
Project description:Cell-specific transcriptomic analysis were performed on PFC endothelial cells of unstressed controls (CTRL), stress-susceptible (SS) and resilient (RES) mice to identify novel genes and pathways involved in stress responses