Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Streptococcus mutans UA159

ABSTRACT: SloR- and Manganese-Responsive sRNAs in Streptococcus mutans

PROVIDER: PRJNA976357 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR24866569.fastq.gz	Fastqsanger.gz
	SRR24866570.fastq.gz	Fastqsanger.gz
	SRR24866571.fastq.gz	Fastqsanger.gz
	SRR24866572.fastq.gz	Fastqsanger.gz
	SRR24866573.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 20

Similar Datasets

Streptococcus mutans UA159 control vs. Streptococcus mutans UA159 supplemented with 20 uM 4,5-dihydroxy-2,3-pentadione (DPD) at 3 different pH values

Project description:Transcriptional profiling of early logarithmic phase culture (O.D=0.2-0.3) of Streptococcus mutans UA159 comparing control of untreated Streptococcus mutans UA159 bacteria with Streptococcus mutans UA159 bacteria spplemented with 20µM synthetic DPD (pre-AI-2) which regulates gene expression via AI-2 quorum sensing system.Three compairisons were performed at pHs of 7,6 and 5.

2010-07-29 | GSE23159 | GEO

Streptococcus mutans UA159

Project description:Streptococcus mutans SMU.243

| PRJNA812614 | ENA

Identification of the phosphotransacetylase (pta) and acetate kinase (ackA) regulons in Streptococcus mutans UA159

Project description:Transcriptional comparisons between wild-type Streptococcus mutans UA159 and two mutant strains (∆ackA and ∆ackA pta).

2013-05-11 | GSE46835 | GEO

Streptococcus mutans UA159

Project description:Streptococcus mutans UA159 Genome sequencing

| PRJNA1043687 | ENA

Streptococcus mutans UA159

Project description:Streptococcus mutans UA159 Raw sequence reads

| PRJNA1066076 | ENA

Streptococcus mutans UA159

Project description:Streptococcus mutans UA159 Raw sequence reads

| PRJNA357631 | ENA

Streptococcus mutans UA159

Project description:Streptococcus mutans UA159 Raw sequence reads

| PRJNA408134 | ENA

Streptococcus mutans UA159

Project description:Streptococcus mutans UA159 Raw sequence reads

| PRJNA484593 | ENA

Streptococcus mutans UA159; 10 mM Glucose Versus 100 mM Glucose

Project description:Transcriptional Profiling of Streptococcus mutans UA159 Grown in Continuous Culture using TV Media Supplemented With 10 mM vs 100 mM Glucose. The genetic and phenotypic responses of Streptococcus mutans, an organism known to be strongly associated with the development of dental caries, to changes in carbohydrate availability were investigated. S. mutans UA159 or a derivative of UA159 lacking ManL, which is the EIIAB component (EIIABMan) of a mannose/glucose permease of the phosphoenolpyruvate:sugar phosphotransferase system (PTS) and a dominant effector of catabolite repression, were grown in continuous culture to steady-state in conditions of excess (100 mM) or limiting (10 mM) glucose. Microarrays using RNA from S. mutans UA159 revealed that 174 genes were differentially expressed in response to changes in carbohydrate availability (P < 0.001). Glucose-limited cells possessed higher PTS activity, could acidify the environment more rapidly and to a greater extent, and produced more ManL protein than cultures grown with excess glucose. Loss of ManL adversely affected carbohydrate transport and acid tolerance. Comp arison of the HPr protein in S. mutans UA159 and the manL deletion strain indicated that the differences in behaviors of the strains were not due to major differences in HPr pools or HPr phosphorylation status. Therefore, carbohydrate availability alone can dramatically influence the expression of physiologic and biochemical pathways that contribute directly to the virulence of S. mutans, and ManL has a profound influence on this behavior. Two-condition experiment, growth in 10 mM vs 100 mM glucose. Biological replicates: 3 per condition, independently grown and harvested. One replicate per array

2013-12-03 | E-GEOD-51362 | biostudies-arrayexpress