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Analysis of transcriptional response changes in rats after treatment with 3-Methylcholanthrene Rats were treated with 3-methylcholanthrene (MC) (100 umol/kg) in corn oil (CO) (2 ml/kg), or were given equal volumes of CO, i.p., once daily for 4 days. At 1, 15, and 28 day time points, the animals wer...
ORGANISM(S): Rattus norvegicus 
Analysis of transcriptional response changes in rats after treatment with 3-Methylcholanthrene Keywords: toxicity
ORGANISM(S): Rattus norvegicus Mus musculus 
2005-12-22 | GSE3175 | GEO
Gene expression analysis of human lymphoblastoid TK6 cells exposed to the carcinogen 3-methylcholanthrene (3-MCA) was conducted. The information entropy of the transcriptome was measured to assess whether a change with biological significance occurred in TK6 cells exposed to 3-MCA. Pathway and liter...
ORGANISM(S): Homo sapiens 
2026-03-17 | GSE324658 | GEO
3-methylcholanthrene exposed TK6 cells
DNA methylation and hydroxymethylation mediated gene expression regulation network involved in 3-methylcholanthrene induced lung cell malignant transformation
3-Methylcholanthrene treated Rat
Expression analysis of colonic neurons stimulated with AhR agonist (3-methylcholanthrene)
3-methylcholanthrene (3-MCA) is a typical representative PAH. It has strong toxicity and is a typical chemical carcinogen. However, the epigenetic mechanisms underlying 3-MCA-induced tumourigenesis are largely unknown. In this study, a model of the 3-MCA-induced malignant transformation of human bro...
ORGANISM(S): Homo sapiens 
2019-12-31 | GSE142718 | GEO
Using the GENIPOL flounder cDNA microarray, we assessed the temporal transcriptomic responses of Platichthys flesus to model toxicants over a 16 day timespan. Immature fish were treated by intraperitoneal injection with cadmium chloride (50 micrograms/kg in saline), 3-methylcholanthrene (25mg/kg in ...
ORGANISM(S): synthetic DNA 
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