aging biomarkers

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Unknown (5328)
Genomics (208)
Transcriptomics (133)
Proteomics (82)
Methylation profiling (24)
Metabolomics (18)
Genomic (8)
Other (4)
Clinical (2)

Organisms

Homo sapiens (132)
Mus musculus (53)
Schizosaccharomyces pombe (49)
Human immunodeficiency virus 1 (49)
Rattus norvegicus (9)
Drosophila melanogaster (7)
Caenorhabditis elegans (4)
Macaca fascicularis (3)
Anopheles gambiae (2)
Oncorhynchus mykiss (2)
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gut metagenome (1)
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Homo (1)

Organisms

Homo sapiens (77)
Mus musculus (35)
Rattus norvegicus (5)
Canis lupus familiaris (4)
Drosophila melanogaster (4)
Caenorhabditis elegans (4)
Microcebus murinus (1)
Heterocephalus glaber (1)
Prunus dulcis (1)
Macaca fascicularis (1)
Oncorhynchus mykiss (1)
feces metagenome (1)
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Saccharomyces cerevisiae (1)

Repository

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pride (49)
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Tissue

Blood plasma (7)
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Cell culture (5)
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IgG short lived plasma cell (1)
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Disease

Glaucoma (2)
Alzheimer's disease (2)
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Control (1)
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Colorectal Neoplasms (1)
Not Available (1)
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Muscular atrophy (1)
Neuronal ceroid lipofuscinosis 3 (1)
Hydrocephalus (1)
Barrett's esophagus (1)
Age related macular degeneration (1)
Cutaneous malignant melanoma 1 (1)
Plasmodium falciparum malaria (1)
Osteoarthritis (1)
Cachexia (1)
Malignant neoplasm of ovary (1)
Parkinson's disease (1)
Glioblastoma (1)
Chronic kidney disease (1)
Human immunodeficiency virus infectious disease (1)

Technology Type

Mass Spectrometry (49)
Shotgun proteomics (21)
Bottom-up proteomics (16)
Mass spectrometry (7)
Mass spectrometry assay (6)
Data-dependent acquisition (5)
NMR spectroscopy (4)
Data-independent acquisition (4)
SWATH MS (3)
Gel-based experiment (2)
Top-down proteomics (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
ILLUMINA, HiSeq X Ten (1)
ILLUMINA, Illumina HiSeq 2500 (1)
MeDIP-seq (1)
Illumina HiSeq 2500 (1)
NMR spectroscopy assay (1)
Olink affinity proteomics (1)
Affinity proteomics (1)
SRM/MRM (1)
Affinity purification coupled with mass spectrometry proteomics (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (5)
Liquid Chromatography MS - negative - reverse phase (4)
TripleTOF 6600 (3)
TripleTOF 5600 (3)
Nuclear Magnetic Resonance (NMR) - (3)
Liquid Chromatography MS - positive - hilic (3)
Q Exactive (2)
Orbitrap Fusion (2)
Orbitrap Fusion Lumos (2)
Liquid Chromatography MS - negative - hilic (2)
Illumina HiSeq 2500 (1)
Illumina HiSeq 2000 (1)
NextSeq 500 (1)
Instrument (1)
Exploris 480 (1)
OrbiTrap Exactive Q HF (1)
LTQ Orbitrap XL (1)
Orbitrap Exploris 480 (1)
Orbitrap Eclipse (1)
Quattro Premier XE (Waters) (1)
Gas Chromatography MS - negative - medium-polarity (1)
Liquid Chromatography MS - NEG - reverse phase (1)
Liquid Chromatography MS - POS - reverse phase (1)
SYNAPT HDMS (Waters) (1)
API 5500 QTRAP (AB Sciex) (1)
Bruker (1)
Xevo G2 QTOF (Waters) (1)
Gas Chromatography MS - positive (1)
Nuclear Magnetic Resonance (NMR) (1)
Liquid Chromatography MS - negative (1)

Publication Date

2025 (40)
2026 (38)
2024 (27)
2021 (22)
2014 (20)
2013 (19)
2015 (18)
2023 (13)
2022 (13)
2020 (12)
2016 (12)
2018 (8)
2010 (7)
2019 (7)
2017 (6)
2012 (5)
2011 (3)
2009 (3)
2008 (3)
2005 (1)
2007 (1)

CHEBI ID

CHEBI:30769 (5)
CHEBI:27266 (5)
CHEBI:25017 (5)
CHEBI:42255 (4)
CHEBI:16243 (4)
CHEBI:15354 (4)
CHEBI:16737 (4)
CHEBI:16856 (4)
CHEBI:15741 (4)
CHEBI:26271 (4)
CHEBI:16449 (4)
CHEBI:18186 (4)
CHEBI:7916 (4)
CHEBI:4806 (3)
CHEBI:15584 (3)
CHEBI:28499 (3)
CHEBI:68352 (3)
CHEBI:90 (3)
CHEBI:30778 (3)
CHEBI:17489 (3)
CHEBI:16634 (3)
CHEBI:18089 (3)
CHEBI:17521 (3)
CHEBI:15724 (3)
CHEBI:16919 (3)
CHEBI:30915 (3)
CHEBI:27480 (3)
CHEBI:20067 (3)
CHEBI:32816 (3)
CHEBI:32806 (3)

Metabolite Name

Creatinine (5)
Picolinic acid (4)
Spermidine (4)
Deoxycholic acid (4)
Phosphocreatine (4)
Succinic acid (4)
Creatine (4)
Citric acid (4)
Anserine (4)
Hypoxanthine (4)
Uracil (4)
Hippuric acid (4)
Cytidine (4)
Guanosine (4)
2,4-Dichlorophenol (3)
Dimethylbenzimidazole (3)
13,14-Dihydro-15-keto-PGE2 (3)
Epiandrosterone (3)
3-Sulfinoalanine (3)
Calcimycin (3)
5-Aminoimidazole-4-carboxamide (3)
Orotidylic acid (3)
Sulfasalazine (3)
Deoxycorticosterone acetate (3)
D-2-Hydroxyglutaric acid (3)
Anastrozole (3)
Cymarin (3)
Trehalose 6-phosphate (3)
Galacturonic acid (3)
Gardenoside (3)

First Public Date

2025 (37)
2026 (29)
2024 (20)
2014 (20)
2023 (14)
2020 (11)
2021 (6)
2018 (6)
2017 (6)
2022 (5)
2019 (5)
2016 (5)
2015 (5)
2013 (4)

Study status

Not provided (1)
Recruiting (1)

Study type

Transcription profiling by array (37)
Methylation profiling by array (13)
Transcription profiling by RT-PCR (5)
RNA-seq of non coding RNA (4)
Unknown experiment type (1)
Animal - One-color microarray (1)
ChIP-chip by array (1)
MicroRNA profiling by high throughput sequencing (1)
DNA-seq (1)
Proteomic profiling by array (1)
Methylation profiling by high throughput sequencing (1)
Observational (1)
Interventional (1)

Release Date

2025 (882)
2024 (694)
2023 (670)
2022 (651)
2021 (584)
2020 (475)
2019 (312)
2018 (250)
2017 (191)
2016 (153)
2015 (130)
2026 (108)
2014 (94)
2013 (57)
2012 (40)
2011 (39)
2010 (23)
2009 (22)
2008 (10)
2007 (4)
2006 (3)
2005 (1)
2004 (1)

Lab affiliation

University of Liverpool (3)
The Guomics Laboratory for Proteome Complexity Science, School of Medicine, School of Life Sciences, Westlake University，Shilongshan Road No.18, Cloud Town, Xihu District, Hangzhou, Zhejiang, China. (1)
PI The Wistar Institute, Philadelphia, PA, USA; (1)
Aging Institute, University of Pittsburgh School of Medicine/UPMC (1)
Traumatic Brain Injury Research, Roskamp Institute, Sarasota, FL, USA (1)
National Institut on Aging, NIH, Baltimore MD, USA (1)
Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea (1)
second xiangya hospital central south university (1)
Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming, China；State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China (1)
Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming, China State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China (1)
L V Prasad Eye Institute, Mithu Tulsi Chanrai Campus Patia, Bhubaneswar (1)
Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, USA (1)
Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention (1)
Department of Developmental Neurobiology St. Jude Children's Research Hospital (1)
Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02215, USA. (1)
Max Planck Institute for Multidisciplinary Sciences, Bioanalytical Mass Spectrometry Group, Göttingen, Germany University Medical Center Göttingen, Department of Clinical Chemistry, Bioanalytics Group, Göttingen, Germany (1)
Department of Pathology (1)
Jennifer Van Eyk, PhD, FAHA and FISHR Director, Advanced Clinical Biosystems Research Institute Professor, Heart Institute and Department of Medicine, Director, Basic Science for the Barbra Streisand Women's Heart Center Erika Glazer Endowed Chair in Women Heart Cedars Sinai Medical Center 127 S. San Vicente Blvd. Advanced Health Science Pavilion A9307 Los Angeles, CA 90048 and Professor, Departments of Medicine and Biological Chemistry, Johns Hopkins University Baltimore (1)
Chemistry & Biochemistry, University of Maryland, College Park, MD, USA (1)
Jennifer Van Eyk, PhD, FAHA and FISHR Director, Advanced Clinical Biosystems Research Institute Professor, Heart Institute and Department of Medicine, Director, Basic Science for the Barbra Streisand Women's Heart Center Erika Glazer Endowed Chair in Women Heart Cedars Sinai Medical Center 127 S. San Vicente Blvd. Advanced Health Science Pavilion A9307 Los Angeles, CA 90048 and Professor, Departments of Medicine and Biological Chemistry, Johns Hopkins University (1)
Javier Muñoz, PhD - Head of Proteomics Unit Spanish National Cancer Research Centre (CNIO) Address: Melchor Fernández Almagro, 3. 28029 Madrid. SPAIN Phone: +34 917 328 000 Ext. 3110 (1)
SULFAGING group; Leibniz Institute for Analytica Sciences - ISAS - eV. Dortmund, GERMANY (1)
Affiliation: Division of Cell Matrix Biology & Regenerative Medicine, The University of Manchester [Data also submitted and owned by Dr Matiss Ozols (matiss.ozols@manchester.ac.uk)] (1)
Department Functional Proteomics Medizinisches Proteom-Center Ruhr-University Bochum Building ProDi Gesundheitscampus 4 44780 Bochum Germany (1)
Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA Singapore-MIT Alliance for Research and Technology, Antimicrobial Resistance Interdisciplinary Research Group, Campus for Research Excellence and Technological Enterprise, Singapore 138602, Singapore (1)
Bone and Cartilage Research Unit, Arthropôle Liège, University of Liège, Liège, Belgium (1)
Johns Hopkins School of Nursing, Baltimore, Maryland Johns Hopkins School of Medicine, Baltimore, Maryland (1)
Department of Pathophysiology, Key Laboratory of Ministry of Education for Neurological Disorders, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (1)
SULFAGING group; Leibniz Institute for Analytical Sciences - ISAS - eV. Dortmund, GERMANY (1)
Professor, Chemistry, Duke University (1)

Location

Germany (1)

Keyword

Frailty (1)
Pharmacokinetics (1)
Capecitabine (1)

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1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

Neutrophil function declines with age, but little is known about the changes in neutrophil metabolism that take place in robust older people and older people with frailty. We used ¹H-NMR spectroscopy to investigate the metabolomic and lipidomic profiles of blood neutrophils from healthy y...

2026-03-26 | MTBLS6055 | MetaboLights

Epigenetic Biomarkers of Aging

PRJNA875201 | ENA

Epigenetic Biomarkers of Aging

PRJNA875202 | ENA

Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice

It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase 5 gene, Fmo5, slows metabolic ageing via pleiotropic effects. We have now used an NMR-based metabonomics approach to study the effects of ageing directly on the metabolic profiles of urine and plasma from male,...

2018-06-20 | MTBLS667 | MetaboLights

Protein Catabolites as Blood-Based Biomarkers of Aging Physiology: Findings From the Dog Aging Project.

Not available

S-EPMC12611326 | biostudies-literature

Comprehensive Metabolic Profiling of Age-Related Mitochondrial Dysfunction in the High-Fat-Fed ob/ob Mouse Heart

The ectopic deposition of fat is thought to lead to lipotoxicity and has been associated with mitochondrial dysfunction and diabetic cardiomyopathy. We have measured mitochondrial respiratory capacities in the hearts of ob/ob and wild-type mice on either a regular chow (RCD) or high-fat (HFD) diet a...

2015-11-17 | MTBLS173 | MetaboLights

Dynamics of biomarkers in relation to aging and mortality.

Not available

S-EPMC4899173 | biostudies-literature

The Leiden Longevity Study: Identification of biomarkers of the rate of ageing

The aim of the study is to identify genetic mechanisms of longevity and to characterize their interaction with the environment. Using the results the future health of people without familial longevity can be improved in old age. Long-lived siblings of European descent were recruited together with th...

2019-07-11 | MTBLS974 | MetaboLights

DNA methylation profiling of the Biomarkers of Aging Consortium Cohort

PRJNA1032590 | ENA

Transcriptional analysis of PBMCs reveals sex specific changes in the aging of the immune system

Aging and sex have a strong influence on the functional capacity of the immune system. In general, the immune response in females is stronger than that in males, but there is little information about the effect of aging on this difference. To address this question, we performed a transcriptomic anal...

ORGANISM(S): Homo sapiens

2015-01-22 | E-GEOD-65219 | biostudies-arrayexpress

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