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MetabolomicsAmniotic-fluid metabolomics identifies phospholipid remodeling as a metabolic signature of intrauterine exposure in pregnancies with polycystic ovary syndrome
Background: Polycystic ovary syndrome is associated with metabolic and hormonal disturbances during pregnancy, but whether these alterations are reflected in the fetal intrauterine exposure environment remains incompletely understood. This study aimed to identify polycystic ovary syndrome-related in...
2026-07-25 | MTBLS14946 | MetaboLights
MetabolomicsIdentification of amniotic fluid metabolomic and placental transcriptomic changes associated with abnormal development of cloned pig fetuses
Piglets cloned by somatic cell nuclear transfer (SCNT) show a high incidence of malformations and a high death rate during the perinatal period. To investigate the underlying mechanisms for abnormal development of cloned pig fetuses, we compared body weight, amniotic fluid (AF) metabolome, and place...
2020-01-08 | MTBLS666 | MetaboLights
MetabolomicsMetabolomics highlights reduced glutamate and acetylcarnitine in the amniotic fluid of cytomegalovirus-infected pregnant women

Cytomegalovirus (CMV) is a ubiquitous infectious agent that causes significant morbidity in immunosuppressed hosts and is the most common cause of neonatal congenital deafness.An infection acquired during pregnancy can be vertically transmitted to the fetus and cause permanent sequelae in the new...

2025-09-12 | MTBLS12415 | MetaboLights
MetabolomicsRat amniotic fluid metabolomics
Not available
ORGANISM(S): Rattus norvegicus 
ST000749 | MetabolomicsWorkbench
TranscriptomicsTranscriptome adaptation of group B Streptococcus to growth in human amniotic fluid
We have discovered that GBS significantly remodels its transcriptome in response to exposure to human amniotic fluid. A large number of the affected genes are of unknown function, which means that much remains to be learned about the full influence of amniotic fluid on GBS. The majority of the obse...
ORGANISM(S): Streptococcus agalactiae 
2010-05-18 | E-GEOD-14456 | biostudies-arrayexpress
MetabolomicsRat amniotic fluid metabolomics (part II)
Not available
ORGANISM(S): Rattus norvegicus 
ST000750 | MetabolomicsWorkbench
ProteomicsKH: Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage
Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage
ORGANISM(S): Mus Musculus (mouse) 
2023-04-13 | PXD024377 | JPOST Repository
TranscriptomicsThe amniotic fluid transcriptome: a source of novel information about human fetal development
Amniotic fluid (AF) is a complex biological material that provides a unique window into the developing human. Residual AF supernatant contains cell-free fetal RNA. The objective of this study was to develop an understanding of the AF core transcriptome by identifying the transcripts ubiquitously pre...
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-33168 | biostudies-arrayexpress
MetabolomicsThe maturity in fetal pigs using a multi-fluid metabolomic approach
In mammalian species, the first days after birth are an important period for survival and the rates of mortality before weaning are high. In pigs, the perinatal deaths average 20% of the litter, with important economic and societal consequences. Among the factors influencing piglet survival at birth...
2020-07-07 | MTBLS1541 | MetaboLights
TranscriptomicsValproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach
Induced pluripotent stem cells (iPSCs) with potential for therapeutic applications can be derived from somatic cells via ectopic expression of a set of limited and defined transcription factors. However, due to risks of random integration of the reprogramming transgenes into the host genome, the low...
ORGANISM(S): Homo sapiens 
2012-07-23 | E-GEOD-26940 | biostudies-arrayexpress
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