antibody-antigen binding

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Transcriptomics (4477)
Unknown (3778)
Genomics (497)
Proteomics (227)
Metabolomics (16)
Other (13)
Models (1)
Multiomics (1)

Organisms

Homo sapiens (1960)
Mus musculus (1429)
Drosophila melanogaster (425)
Rattus norvegicus (130)
Arabidopsis thaliana (89)
Saccharomyces cerevisiae (69)
Danio rerio (47)
Sus scrofa (40)
Bos taurus (39)
Gallus gallus (35)
Caenorhabditis elegans (27)
Zea mays (19)
Oryza sativa (19)
Canis lupus familiaris (16)
Streptococcus pneumoniae D39 (16)
Macaca mulatta (16)
Escherichia coli (14)
Oncorhynchus mykiss (12)
Oryza sativa Japonica Group (12)
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Staphylococcus aureus (10)
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Salmo salar (8)
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Equus caballus (6)
Glycine max (6)
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 (5)
Colinus virginianus (5)
Salmonella enterica subsp. enterica serovar Typhimurium (5)

Organisms

Mus musculus (51)
Homo sapiens (46)
Macaca mulatta (6)
Saccharomyces cerevisiae (2)
Escherichia phage T7 (1)
Sus scrofa (1)

Repository

biostudies-arrayexpress (4812)
ENA (146)
geo (77)
pride (61)
EGA (51)
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jPOST (22)
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PanoramaPublic (7)
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EVA (1)

Tissue

Cell culture (11)
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Blood (3)
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Blood plasma (2)
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Bud (1)
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Spermatogonium (1)

Disease

Normal (17)
Chronic lymphocytic leukemia (4)
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CLL (1)
Arrhythmias and right ventricular dysfunction (1)
GIP-dependent Cushing's syndrome (1)
HPV positive (1)
Osteosarcoma subtype fibroblastic (1)
High grade glioblastoma (1)
SMARD1 (1)
Cocaine addiction (1)
Primary effusion lymphoma (PEL) (1)
DNA damage (1)
Diabetes mellitus type 1 (1)
Chronic lymphocytic leukemia (CLL) (1)
Uninfected (1)
Diffuse large B-cell lymphoma (1)
Schizophrenia (1)
Colon Cancer (1)
Primary tumor (1)
Rheumatoid arthritis (1)
Acute lymphoblastic leukemia (1)
Leukemia (1)
Coronary artery disease (1)
Renal cell carcinoma (1)
Osteosarcoma (1)
Glioblastoma (1)
Prostate carcinoma (1)
Collagen induced arthritis (1)

Technology Type

Mass Spectrometry (61)
Bottom-up proteomics (20)
Shotgun proteomics (19)
Affinity purification coupled with mass spectrometry proteomics (13)
Mass spectrometry (9)
Mass spectrometry assay (7)
Chemical cross-linking coupled with mass spectrometry proteomics (5)
Data-independent acquisition (4)
MSE (4)
All-ion fragmentation (3)
Data-dependent acquisition (3)
HDMSE (3)
Top-down proteomics (3)
Illumina HiSeq 2500, Illumina HiSeq 4000, ILLUMINA (1)
Illumina Oncoscan Array (1)
ILLUMINA, NextSeq 500 (1)
Illumina HiSeq 2000 (1)
Illumina MiSeq (1)
Affinity proteomics (1)
Gel-based experiment (1)
PAcIFIC (1)

Instrument Platform

Illumina NovaSeq 6000 (87)
NextSeq 500 (43)
Illumina HiSeq 4000 (34)
Illumina HiSeq 2500 (32)
Illumina HiSeq 2000 (29)
NextSeq 2000 (15)
Illumina MiSeq (10)
Illumina NovaSeq X (9)
NextSeq 550 (8)
Illumina Genome Analyzer II (3)
10x Genomics Chromium (2)
BAS-5000 [FUJIFILM] (2)
Illumina Genome Analyzer IIx (2)
Ion Torrent Proton (2)
HiSeq X Ten (2)
Illumina HiSeq 1500 (2)
Illumina HiSeq 3000 (2)
Illumina HiSeq 2000 platform (1)
Hamamatsu Nanozoomer S60 (1)
TruSeq stranded Total RNA kit (1)
UltraTM RNA Library Prep Kit (NEBNext®) (1)
MiRNeasy Mini Kit from Qiagen® (1)
Illumina NextSeq2000 (2x100bp) (1)
Digital Alliance of Canada (1)
AAV-CRISPR (1)
10X Dual Index Kit (1)
10X Chromium Next GEM Single-Cell 3' Kit v3.1 (1)
CellRanger v2.1.0 (1)
10X Genomics Single Cell, V3.1 (1)
KAPA EvoPrep Kit (1)

Publication Date

2013 (772)
2015 (717)
2010 (685)
2011 (572)
2014 (497)
2012 (461)
2008 (231)
2016 (223)
2009 (172)
2007 (102)
2022 (94)
2026 (77)
2025 (67)
2023 (59)
2021 (52)
2024 (49)
2005 (39)
2020 (35)
2006 (32)
2017 (27)
2019 (24)
2018 (24)
2004 (10)
2003 (6)
2002 (3)

CHEBI ID

CHEBI:15428 (4)
CHEBI:32816 (4)
CHEBI:16919 (4)
CHEBI:30769 (4)
CHEBI:16796 (3)
CHEBI:91315 (3)
CHEBI:15611 (3)
CHEBI:16344 (3)
CHEBI:15676 (3)
CHEBI:16708 (3)
CHEBI:16742 (3)
CHEBI:17562 (3)
CHEBI:16530 (3)
CHEBI:15741 (3)
CHEBI:17268 (3)
CHEBI:28683 (3)
CHEBI:17821 (3)
CHEBI:16865 (3)
CHEBI:30745 (3)
CHEBI:15727 (3)
CHEBI:17196 (3)
CHEBI:17115 (3)
CHEBI:16235 (3)
CHEBI:16335 (3)
CHEBI:17568 (3)
CHEBI:15940 (3)
CHEBI:16467 (3)
CHEBI:18019 (3)
CHEBI:17203 (3)
CHEBI:18300 (3)

Metabolite Name

Chenodeoxycholic acid (3)
Citrulline (3)
Succinic acid (3)
Fumaric acid (3)
Citric acid (3)
Guanine (3)
Suberic acid (3)
Adipic acid (3)
Creatine (3)
Tryptophan (3)
Cosmosiin (2)
Taurochenodeoxycholic acid (2)
Methylcysteine (2)
N-Acetyl-D-glucosamine (2)
Hydroxypropionic acid (2)
Oxoglutaric acid (2)
L-Cystine (2)
Glycodeoxycholic acid (2)
Leucine (2)
Indoleacetic acid (2)
Threonic acid (2)
Phomopsin A (2)
Xylose (2)
4-Vinylphenol (2)
Taurodeoxycholic acid (2)
Oxalic acid (2)
N-Acetylalanine (2)
Ketoleucine (2)
Dimethylglycine (2)
Glycine (2)

IsPrivate

False (1)

Submitter Keywords

FAIR-AIML (1)
Machine Learning Model (1)

First Public Date

2026 (22)
2023 (21)
2025 (19)
2022 (17)
2024 (13)
2017 (11)
2014 (10)
2021 (8)
2016 (8)
2020 (7)
2018 (4)
2019 (3)
2015 (3)

Classification

viruses (1)

Modelling Approach

Other (1)

Study type

Transcription profiling by array (2891)
RNA-seq of coding RNA (543)
ChIP-chip by tiling array (324)
ChIP-seq (266)
Unknown experiment type (130)
RNA-seq of non coding RNA (97)
RNA-seq of coding RNA from single cells (82)
Proteomic profiling by array (80)
Other (71)
Methylation profiling by array (54)
Comparative genomic hybridization by array (49)
Transcription profiling by SAGE (36)
ChIP-chip by array (28)
Transcription profiling by RT-PCR (19)
Methylation profiling by high throughput sequencing (17)
Transcription profiling by tiling array (16)
CUT&RUN (10)
Animal - High-throughput sequencing (9)
Genotyping by array (9)
DNA-seq (8)
RNA-seq of total RNA (8)
Antigen profiling (7)
MicroRNA profiling by high throughput sequencing (6)
High-throughput sequencing (5)
MicroRNA profiling by array (5)
Human - High-throughput sequencing (4)
ATAC-seq (4)
Differential (3)
RIP-seq (3)
Transcription profiling by MPSS (2)

Release Date

2013 (879)
2015 (851)
2010 (744)
2011 (649)
2014 (622)
2012 (544)
2022 (502)
2023 (410)
2021 (402)
2016 (402)
2025 (363)
2024 (336)
2020 (312)
2008 (257)
2018 (240)
2009 (227)
2019 (218)
2017 (216)
2007 (125)
2026 (102)
2005 (56)
2006 (50)
2003 (21)
2004 (16)
1999 (11)
2001 (10)
2002 (8)
2000 (8)
1998 (6)
1997 (2)

Lab affiliation

Aarhus University Department of Biomedicine DK-8000 Aarhus (3)
Department of Medicinal Chemistry, University of Washington (3)
Department of Molecular and Translational Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology; Warsaw, Poland (2)
Institut Pasteur of Shanghai (2)
Institute of Lung Biology and Disease and Comprehensive Pneumology Center, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, German (2)
Proteome Center Rostock Department for Proteome Research Institute of Immunology Medical Faculty and Natural Science Faculty University of Rostock Schillingallee 69 18057 Rostock Germany (2)
University of Edinburgh, Institute of Genetics and Molecular Medicine, Edinburgh, Scotland, United Kingdom, EH4 2XR (2)
University of Toronto (2)
Arkana Laboratories, Little Rock, Arkansas, USA (1)
Associate Professor of Neuroscience and BIO5 Institute University of Arizona (1)
Bioinformatics Solutions Inc., Waterloo, Ontario, Canada (1)
Biological Mass Spectrometry Facility, Center for Biomedical Research Support, The University of Austin at Texas (1)
Cancer Genetics Group Josep Carreras Leukaemia Research Institute Can Ruti Campus Ctra de Can Ruti, Camí de les Escoles s/n 08916 Badalona, Barcelona Spain (1)
Center for Proteomics and Metabolomics, LUMC, Leiden, The Netherlands (1)
Center for Proteomics and Metabolomics, Leiden University Medical Center (1)
Centre for Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany (1)
Core Facilitz Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen (1)
DEPARTMENT OF TROPICAL MEDICINE,SCHOOL OF TROPICAL MEDICINE, KOLKATA, WEST BENGAL, INDIA (1)
DIADE, IRD, CIRAD, Université de Montpellier, Montpellier, France (1)
Department of Chemistry, University of Washington, Seattle, WA (1)
Department of Microbiology & Immunology, National University of Singapore, Singapore (1)
Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA (1)
Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 3, Halle/Saale D-01620, Germany Center for Structural Mass Spectrometry, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 3, Halle/Saale D-01620, Germany (1)
Department of Pharmacy, University of Copenhagen (1)
Director, Proteome Center Rostock, University of Rostock, Germany (1)
Division of Infection Medicine, Department of Clinical Sciences, Faculty of Medicine, Lund University, Klinikgatan 26, 222 42 Lund, Sweden (1)
Division of Pediatric Hematology and Oncology, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland (1)
EDyP (1)
Faculty of Medicine, Tel Aviv University, Israel (1)
Guangdong Provincial Key Laboratory of Pathogenic Biology and Epidemiology for Aquatic Economic Animal, Key Laboratory of Control for Disease of Aquatic Animals of Guangdong Higher Education Institutes, College of Fishery, Guangdong Ocean University, Zhanjiang, P.R. China. (1)

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Profiling antibody function on antigen arrays

Humoral immune responses are traditionally characterized by determining the presence and quality of antibodies specific for certain antigens. Arraying of large numbers of antigens allows the parallel measurement of antibodies, generating patterns called antibody profiles. Functional characterization...

ORGANISM(S): Homo sapiens

2010-05-15 | E-GEOD-12943 | biostudies-arrayexpress

The Trypanosoma cruzi Antigen and Epitope Atlas: discovery of antibody specificities in human Chagas Disease patients across human populations

These assays represent an antigen discovery screening, and epitope mapping characterization. In this screening two complete proteomes from Trypanosoma cruzi, from two different strains (CL-Brener, Sylvio X10), were displayed in the form of short peptides (tiling array, overlapped) and assayed with p...

ORGANISM(S): Homo sapiens

2022-08-20 | E-MTAB-11651 | biostudies-arrayexpress

HDX-MS implicates dynamic CD20 antigen binding to two discontinuous CDR regions in the NCD1.2 monoclonal antibody

A comparative canine-human therapeutics model is being developed in B-cell lymphoma through the generation of a hybridoma cell that produces a murine monoclonal antibody specific for canine CD20. The hybridoma cell produces two light chains, light chain-3 and light chain-7. However, the contribution...

ORGANISM(S): Canis lupus x Canis lupus familiaris

2021-09-09 | PXD018550 | Pride

Hydrogen Deuterium Exchange Mass Spectrometry implicates dynamic CD20 antigen binding to two discontinuous CDR regions in the NCD1.2 monoclonal antibody

ORGANISM(S): Canis lupus x Canis lupus familiaris

2021-09-09 | PXD018510 | Pride

Human Comparative medicine Lymphoma Monoclonal antibody Hdx Adept Phage display Cd20 Lc-ms/ms

High-throughput profiling of antigen-specific antibody secreting cells using an antibody secretion trap (TRAPnSeq)

PRJNA976400 | ENA

RNA-seq of human peripheral blood mononuclear cells following oral cholera vaccination

In this study we performed RNA-seq to identify human transcriptomic signatures associated with antibody responses to an oral cholera vaccine. We isolated total RNA from peripheral blood mononuclear cells of vaccinated volunteers who following two priming oral immunisations, had either strong or no a...

ORGANISM(S): Homo sapiens

2021-03-23 | E-MTAB-9069 | biostudies-arrayexpress

The Trypanosoma cruzi Antigen and Epitope Atlas: fine characterization of antibody specificities in human Chagas Disease patients across human populations

These assays represent antibody-binding assays to analyze seroprevalence of antigens and epitopes at the individual level and also to perform fine epitope mapping characterizations. In this screening 392,299 peptides derived from reactive (antigenic) regions of Trypanosoma cruzi proteins were displa...

ORGANISM(S): Homo sapiens

2022-08-20 | E-MTAB-11655 | biostudies-arrayexpress

Learned features of antibody-antigen binding affinity.

Not available

S-EPMC9989197 | biostudies-literature

Epitope mapping of a monoclonal antibody directed against Neisserial Heparin Binding Antigen

PRJNA321411 | ENA

Calcium-dependent antigen binding as a novel modality for antibody recycling by endosomal antigen dissociation.

Not available

S-EPMC4966519 | biostudies-literature

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