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TranscriptomicsExpression data from (bezafibrate treated-wild type, Clock mutant, and PPARalpha-null) mouse liver
A functional interaction between peroxisome proliferator-activated receptor alpha (PPARalpha) and components of the circadian clock has been suggested; however, it remains to be clarified whether those transcriptional factors interact with each other to regulate the expression of their target genes....
ORGANISM(S): Mus musculus 
2010-06-14 | E-GEOD-20513 | biostudies-arrayexpress
TranscriptomicsBezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice
Bezafibrate (BEZ), a pan activator of peroxisome proliferator-activated receptors (PPARs), is generally used to treat hyperlipidemia. Clinical trials on patients suffering from type 2 diabetes indicated that BEZ also has beneficial effects on glucose metabolism, but the underlying mechanisms remain ...
ORGANISM(S): Mus musculus 
2016-06-29 | E-GEOD-79008 | biostudies-arrayexpress
TranscriptomicsExpression data from liver, PFC and amygdala of mice treated with PPAR agonists
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that act as ligand-activated transcription factors. Although prescribed for dyslipidemia and type-II diabetes, PPAR agonists have demonstrated therapeutic properties for several brain disorders, including alcohol depen...
ORGANISM(S): Mus musculus 
2015-04-14 | E-GEOD-67796 | biostudies-arrayexpress
GenomicsGene expression data of bezafibrate treated CD8+ T cells
Gene expression data of bezafibrate treated CD8+ T cells
PRJNA486360 | ENA
UnknownBezafibrate attenuates immobilization-induced muscle atrophy in mice.
Not available
S-EPMC10817916 | biostudies-literature
UnknownMetabolic effects of bezafibrate in mitochondrial disease.
Not available
S-EPMC7059007 | biostudies-literature
GenomicsPotential of Bezafibrate for Combination with Nivolumab in Treatment of Advanced Non-Small Cell Lung Cancer
Potential of Bezafibrate for Combination with Nivolumab in Treatment of Advanced Non-Small Cell Lung Cancer
PRJNA835880 | ENA
UnknownBezafibrate administration improves behavioral deficits and tau pathology in P301S mice.
Not available
S-EPMC3490516 | biostudies-literature
UnknownBezafibrate alleviates diabetes-induced spermatogenesis dysfunction by inhibiting inflammation and oxidative stress.
Not available
S-EPMC10963653 | biostudies-literature
UnknownBezafibrate confers neuroprotection in the 5xFAD mouse model of Alzheimer's disease.
Not available
S-EPMC10528941 | biostudies-literature
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