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MetabolomicsPhototrophic biofilm assembly in microbial-mat-derived unicyanobacterial consortia: model systems for the study of autotroph-heterotroph interactions
Microbial autotroph-heterotroph interactions influence biogeochemical cycles on a global scale, but the diversity and complexity of natural systems and their intractability to in situ manipulation make it challenging to elucidate the principles governing these interactions. The study of assembling p...
2014-06-24 | MTBLS75 | MetaboLights
GenomicsIn vitro evolution of Pseudomonas aeruginosa AA2 biofilms in the presence of cystic fibrosis lung microbiome members
P. aeruginosa was cultured in a MultiScreen-Mesh plate, which has a filter at the bottom of the wells. The plate was immersed in either in medium alone (control) or in medium inoculated with a mixture of five bacterial strains commonly found in cystic fibrosis sputum (\"microbiome\"). The filter pre...
ORGANISM(S): Pseudomonas aeruginosa 
2019-09-13 | E-MTAB-7331 | biostudies-arrayexpress
MetabolomicsGut microbiome dysbiosis drives metabolic dysfunction in Familial dysautonomia
Familial dysautonomia (FD) is a rare genetic neurologic disorder caused by impaired neuronal development and progressive degeneration of both the peripheral and central nervous systems. FD is monogenic, with >99.4% of patients sharing an identical point mutation in the elongator acetyltransferase co...
2022-12-06 | MTBLS5138 | MetaboLights
ProteomicsGlobal identification of biofilm-specific proteolysis in Candida albicans
The global extracellular protease substrate specificity of C. albicans under biofilm and planktonic (suspension) conditions was determined with a synthetic library of 14-mer peptide substrates using an approach termed Multiplex Substrate Profiling by Mass Spectrometry (MSP-MS). Shotgun proteomics an...
ORGANISM(S): Candida Albicans (ncbitaxon:5476) 
2016-03-09 | MSV000079564 | MassIVE
GenomicsEnvironmental Microbiome Biofilm
Environmental Microbiome Biofilm Metagenome
PRJNA1099917 | ENA
GenomicsMicrobiome of Sewer Biofilm
Microbiome of Sewer Biofilm Metagenome
PRJNA615681 | ENA
ProteomicsImpact of different oral treatments on the composition of the supragingival plaque microbiome
Using a metaproteome approach in addition to a standard plaque-regrowth study, this study examined the impact of different concentrations of lactoperoxidase (LPO) in two lozenge formulations on early plaque formation, microbiome composition, and active biological processes in young orally healthy vo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-29 | MSV000089755 | MassIVE
UnknownGlobal challenges and microbial biofilms: Identification of priority questions in biofilm research, innovation and policy.
Not available
S-EPMC11364012 | biostudies-literature
TranscriptomicsBile-induced biofilm formation in Bacteroides thetaiotaomicron requires magnesium efflux by an RND pump
The study is about the role of Bacteroides thetaiotaomicron in the human gut microbiota, specifically its ability to form biofilms in response to bile salts. The study found that bile induces the expression of certain efflux pumps, and inhibiting these pumps impairs biofilm formation. Among the indu...
ORGANISM(S): Bacteroides thetaiotaomicron 
2024-03-19 | E-MTAB-13460 | biostudies-arrayexpress
ProteomicsProtein expression patterns associated with sucrose-induced dysbiosis are conserved across taxonomically diverse oral microcosm biofilm models of dental caries.
The lesions of enamel caries can be considered as the outcome of dysbiotic changes in the biofilm community of supragingival dental plaque. Demineralization occurs as the cumulative outcome of repeated shifts towards a less diverse microbiota that produces and tolerates a low pH environment in tooth...
ORGANISM(S): Streptococcus mutans 19 
2016-01-04 | PXD003151 | Pride
Dental caries Metaproteomics Oral microbiome Galaxy-p Dysbiosis 
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