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ProteomicsCharacterizing cardiac molecular mechanisms of mammalian hibernation via quantitative proteogenomics.
This study uses advanced proteogenomic approaches in a non-model organism to elucidate cardioprotective mechanisms used during mammalian hibernation. Mammalian hibernation is characterized by dramatic reductions in body temperature, heart rate, metabolism and oxygen consumption. These changes pose s...
ORGANISM(S): Spermophilus tridecemlineatus (Thirteen-lined ground squirrel) 
2015-11-03 | PXD002457 | Pride
Keywords: proteogenomics Heart. Galaxy-p Hibernation 
UnknownDisseminating Metaproteomic Informatics Capabilities and Knowledge Using the Galaxy-P Framework.
Not available
S-EPMC5874766 | biostudies-literature
UnknownUsing Galaxy-P to leverage RNA-Seq for the discovery of novel protein variations.
Not available
S-EPMC4158061 | biostudies-literature
ProteomicsQuantitative proteogenomic characterization of inflamed murine colon tissue using an integrated discovery, verification, and validation proteogenomic workflow
Rag2-/-Il10-/- mice were subjected to infection by Helicobacter hepaticus and allowed to develop long-term infections. Proximal colon tissue was then harvested from the mice for analysis. RNA was isolated from the samples and submitted for transcriptomic analysis; this data was then used to create a...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-19 | PXD028407 | Pride
Mouse Tmt Prm Proximal colon Orbitrap Dda 
MetabolomicsField study of the fire blight resistant cisgenic apple line C44.4.146

Cisgenesis, the genetic modification of a plant with genes from a sexually compatible plant, was used to confer fire blight resistance to the cultivar 'Gala Galaxy' by amendment of the resistance gene FB_MR5, resulting in the line C44.4146. To verify whether cisgenesis changed other tree-, flower...

2022-12-19 | MTBLS5810 | MetaboLights
MetabolomicsExperimental and computational approaches for deep metabolome annotation with application to the ecotoxicological model organism Daphnia magna

Identifying metabolomes with greater coverage and confidence is a critical step towards interpreting the metabolic basis of human and environmental health. Yet for over two decades the field of metabolomics has been inhibited by limited metabolite identification. To address this, we developed the...

MTBLS2273 | MetaboLights
UnknownRadiological and pathological analysis of the galaxy sign in patients with pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma.
Not available
S-EPMC10447172 | biostudies-literature
TranscriptomicsAlarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii
Purpose: The goal of this study is to compare NGS-derived transcriptome profiling of human PBMC infected with T. gondii, PRU and RH strains, (RNA-seq) to not stimulated human PBMC transcriptome (RNA-seq). Methods: After 24h post infection PBMC and non-infected PBMC mRNA profiles were generated by de...
ORGANISM(S): Homo sapiens 
2018-12-01 | GSE119835 | GEO
TranscriptomicsHuman lymphedema tissues exhibit an inflammatory gene expression profile
Lymphedema (LD) is characterized by the accumulation of protein-rich interstitial fluid, lipids and a significant inflammatory cell infiltrate in the limb. It causes a significant morbidity and is a common disabling disease affecting more than 150 million people worldwide, however there is no yet cu...
ORGANISM(S): Homo sapiens 
2023-06-09 | E-MTAB-13019 | biostudies-arrayexpress
UnknownMaking whole genome multiple alignments usable for biologists.
Not available
S-EPMC3157923 | biostudies-literature
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