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ProteomicsLabel-free global proteome profiling of European American and African American bladder tumor patients.
Bladder cancer (BLCA) mortality is higher in African American (AA) patients compared to their European American (EA) counterparts, but the molecular mechanism underlying differences are unknown. . Thus, we performed proteomics analysis of AA and EA BLCA and identified higher mitochondrial OXPHOS spe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-08 | MSV000095559 | MassIVE
ProteomicsFrom Cell Lines To The Clinic: Identifying A Specific Urinary BlCa-EV Signature In Comparative Proteomics Of Bladder Cancer Lysates And Extracellular Vesicles
Background: There is an urgent need for the development of innovative diagnostic and therapeutic strategies in bladder cancer (BlCa) management, due to its significant incidence, mortality and morbidity. Extracellular vesicles (EVs) represent highly promising candidates as biomarkers, as their cargo...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD071837 | Pride
Bladder cancer Proteomics Cell lines Urine Extracellular vesicles 
ProteomicsProteomic Profiling Of Bladder Cancer Patients-Derived Extracellular Vesicles
Extracellular vesicle (EV) proteomics holds great promise for non-invasive cancer biomarker discovery. This study presents the first comprehensive proteomic characterization of EVs from tissue, plasma, and urine, focusing on bladder cancer BlCa. EVs were isolated via ultracentrifugation, and their c...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD062618 | Pride
Extracellular vesicles  proteomics  liquid biopsy  biomarker  bladder cancer 
TranscriptomicsThe UBC-40 Urothelial Bladder Cancer Cell Line Index [gene expression]
This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lines including information on origin, mutation status of genes implicated in bladder cancer (FGFR3, PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental diso...
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-64279 | biostudies-arrayexpress
TranscriptomicsThe UBC-40 Urothelial Bladder Cancer Cell Line Index [copy number variation]
This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lines including information on origin, mutation status of genes implicated in bladder cancer (FGFR3, PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental diso...
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-64572 | biostudies-arrayexpress
ProteomicsMevalonate pathway inhibition affects bladder cancer metastasis
Metastasis is an important factor affecting the prognosis and survival of bladder cancer (BLCA) patients. Our previous study found that the mevalonate pathway is associated with the migratory ability of bladder cancer cells, but the exact mechanism is unclear. Here, we found that BLCA patients with ...
ORGANISM(S): Homo Sapiens 
2024-09-09 | PXD048067 |
TranscriptomicsTranscription profiling of human bladder cancer cell line TCCSUP over-expressing the transcription factor Oct-4 and control-tansfected cells
Comparison of TCCSUP cancer cells transformed with an EGFP control vector vs transcription factor Oct-4 overexpressed line of TCCSUP cancer cells
ORGANISM(S): Homo sapiens 
2008-09-30 | E-MEXP-1378 | biostudies-arrayexpress
ProteomicsDNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC
Hitherto, most studies on POLD1 have mainly focused on the effect of POLD1 inactivation mutation in tumors. Nonetheless, the mechanism underlying high POLD1 expression in tumorigenesis remains elusive. Herein, we substantiated the pro-carcinogenic role of POLD1 in bladder cancer (BLCA) and found tha...
ORGANISM(S): Homo sapiens (Human) 
2023-03-29 | PXD040806 | Pride
Dna polymerase δ (pold1)  bladder cancer (blca)  myc  fbxw7  ubiquitination degradation. 
ProteomicsGlycomics and Glycoproteomics Reveal Distinct Oligomannose Carriers Across Bladder Cancer Stages
Aberrant glycosylation is a hallmark of cancer, offering opportunities to enhance clinical decision-making and enable precise targeting of cancer cells. Nevertheless, alterations in the bladder urothelial carcinoma (BLCA) N-glycome remain poorly characterized. Here, we used in situ N-deglycosylation...
ORGANISM(S): Homo sapiens (Human) 
2025-05-20 | PXD063671 | Pride
Bladder cancer  n-glycomics  n-glycoproteins 
TranscriptomicsExpression data from rat orthotopic bladder cancer
In the development and progression of bladder cancer, there are many genetic changes. We established a SD rat orthotopic bladder cancer model through intravesical instillation of N-methyl-nitrosourea and pathologic diagnosis is bladder transtional cell carcinomal (BTCC). We used microarrays to analy...
ORGANISM(S): Rattus norvegicus 
2016-01-12 | E-GEOD-76702 | biostudies-arrayexpress
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