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MetabolomicsEffect of hypoxia and reoxygenation on the juvenile hooded seal brain lipidome
Not available
ORGANISM(S): Cystophora cristata 
ST002358 | MetabolomicsWorkbench
MetabolomicsEffect of hypoxia and reoxygenation on the adult hooded seal brain lipidome
Not available
ORGANISM(S): Cystophora cristata 
ST002359 | MetabolomicsWorkbench
MetabolomicsSodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (targeted SCFA brain metabolomics)

Neonatal hypoxic-ischemic encephalopathy (HIE) refers to nervous system damage caused by perinatal hypoxia, which is the major cause of long-term neuro-developmental disorders in surviving infants. However, the mechanisms still require further investigation. In this study, we found that the butan...

2022-10-12 | MTBLS4933 | MetaboLights
MetabolomicsSodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)

Neonatal hypoxic-ischemic encephalopathy (HIE) refers to nervous system damage caused by perinatal hypoxia, which is the major cause of long-term neuro-developmental disorders in surviving infants. However, the mechanisms still require further investigation. In this study, we found that the butan...

2022-10-12 | MTBLS4932 | MetaboLights
TranscriptomicsTranscriptional Response of Adult Mouse Brain to Hypoxia
Since normal brain function depends upon continuous oxygen delivery and short periods of hypoxia can precondition against subsequent ischemia, this study examined the effects of brief hypoxia on the whole genome transcriptional response in adult mouse brain. Genomic expression profiling was perfrome...
ORGANISM(S): Mus musculus 
2011-12-30 | E-GEOD-19709 | biostudies-arrayexpress
MetabolomicsElevated brain manganese induces motor disease by upregulating the kynurenine pathway of tryptophan metabolism
Elevated brain levels of the essential metals manganese (Mn), copper, or iron induce motor disease. However, mechanisms of metal-induced motor disease are unclear and treatments are lacking. Elucidating the mechanisms of Mn-induced motor disease is particularly important because occupational and env...
2025-03-31 | MTBLS975 | MetaboLights
ProteomicsHypoxia induced sex-difference in zebrafish brain proteome profile reveals the crucial role of H3K9me3 in recovery from acute hypoxia
Understanding the molecular basis of sex differences in neural response to acute hypoxic insult has profound implications for the effective prevention and treatment of ischemic stroke. Global hypoxic-ischemic induced neural damage has been studied recently under the well-controlled, non-invasive, re...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-02-22 | PXD027528 | Pride
Ipa Sex difference Pathway analysis Itraq Hypoxia-ischemia recovery 
MetabolomicsIntergenerational Association of Gut Microbiota and Metabolism with Perinatal Folate Metabolism and Neural Tube Defects (Brain tissue metabolomics)

Neonatal hypoxic-ischemic encephalopathy (HIE) refers to nervous system damage caused by perinatal hypoxia, which is the major cause of long-term neuro-developmental disorders in surviving infants. However, the mechanisms still require further investigation. In this study, we found that the butan...

2022-12-05 | MTBLS4894 | MetaboLights
TranscriptomicsGene Expression Profile in Developing Mouse Brain Following Chronic Hypoxia Treatment
In this study, we determined the effect of chronic consistent hypoxia (CCH) and chronic intermittent hypoxia (CIH) on global gene expression in cortical and hippocampal region of developing mouse brain using long-oligo beadschip arrays. Keywords: Gene expression profile Control-Cortex: Cortical samp...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-8262 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HeLa cell line response to hypoxia
Oxygen is vital for the development and survival of mammals. In response to hypoxia, the brain initiates numerous adaptive responses at the organ level as well as at the molecular and cellular level, including the alteration of gene expression. Astrocytes play critical roles in the proper function...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3051 | biostudies-arrayexpress
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