262771 Results

Show all   Save search   Copy query
Sort   by:  
 Page size 
MetabolomicsLow-temperature induced neuro-oxidative stress and metabolic reprogramming in the brain of juvenile fourfinger threadfin (Eleutheronema tetradactylum)
This study investigated the effects of low-temperature stress on the brain metabolome of juvenile fourfinger threadfin (Eleutheronema tetradactylum). Using UHPLC-Q-TOF-MS-based untargeted metabolomics, we analyzed brain tissues from fish exposed to 28°C (control) and 18°C for 7 and 14 days. The aim ...
2026-07-22 | MTBLS15103 | MetaboLights
ProteomicsProteome analysis of adult mouse brain capillaries
Isolated brain capillaries are essential for analyzing the changes of protein expressions at the blood-brain barrier (BBB) under pathological conditions. The standard brain capillary isolation methods require the use of at least 5 mouse brains in order to obtain a sufficient amount and purity of bra...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-12 | PXD041770 | JPOST Repository
TranscriptomicsHigh resolution analysis of genomic imprinting in the embryonic and adult mouse brain AND Sex-specific imprinting in the mouse brain
Genomic imprinting results in the preferential expression of the paternal, or maternal allele of certain genes. We have performed a genome-wide characterization of imprinting in the mouse embryonic and adult brain using F1 hybrid mice generated from reciprocal crosses of CASTEiJ and C57BL/6J mice. ...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-22131 | biostudies-arrayexpress
ProteomicsProteome analysis of neonatal mouse brain and brain capillaries
The functions and protein expressions of the blood-brain barrier are changed during brain development after birth. The purpose of the present study was to develop a method to isolate brain capillaries from a single frozen neonatal mouse brain and elucidate the enrichment of brain capillaries by quan...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-12 | PXD039296 | JPOST Repository
TranscriptomicsMicroRNA profiling of brain metastasis competent cell-derived exosomes
Objective of this work was to characterize the miRNA profile of exosomes isolated from brain-homing cell lines (MDA-MB-231BR, CTC1BMSM, and 70W) with their respective parental non-brain metastatic cell lines (MDA-MB-231P, CTC1P and MeWo). Exosomes derived from the six cell lines were isolated. Brain...
ORGANISM(S): Homo sapiens 
2013-07-16 | E-GEOD-48934 | biostudies-arrayexpress
TranscriptomicsTranscriptional Response of Adult Mouse Brain to Hypoxia
Since normal brain function depends upon continuous oxygen delivery and short periods of hypoxia can precondition against subsequent ischemia, this study examined the effects of brief hypoxia on the whole genome transcriptional response in adult mouse brain. Genomic expression profiling was perfrome...
ORGANISM(S): Mus musculus 
2011-12-30 | E-GEOD-19709 | biostudies-arrayexpress
TranscriptomicsAnalysis of gene expression profiling of normal retina and brain cortices
Using a canine custom retinal cDNA microarray our aim is to identify normal gene expression profiling for retina and frontal, occipital and temporal brain cortices Total RNA was isolated using Trizol reagent (Invitrogen, Carlsbad, CA) and further purified by Rneasy mini kit (Qiagen, Valencia, CA). P...
ORGANISM(S): Canis familiaris 
2010-07-01 | E-GEOD-5208 | biostudies-arrayexpress
ProteomicsMicroglia and brain organoids
iPSC-derived microglia export cholesterol to neuronal cells in human brain organoids and promote their maturation
ORGANISM(S): Homo Sapiens (human) 
2023-05-19 | PXD042344 | JPOST Repository
TranscriptomicsAn RNAi Screen Identifies TRRAP as a Regulator of Brain Tumor-Initiating Cell Differentiation
Glioblastoma multiforme is the most common and most aggressive type of primary brain tumor. The brain-infiltrative character of glioblastoma makes complete surgical removal of the tumor impossible and neither radiation nor current chemotherapy provide cure. Recent evidence shows that glioblastoma mu...
ORGANISM(S): Homo sapiens 
2011-03-14 | E-GEOD-27931 | biostudies-arrayexpress
TranscriptomicsmRNA expression of brain endothelial cells
To investigate the mRNA expression after extracellular vesicles or miRNA treatement, global gene expression analysis was performed in endothelial cells after the transfection of N.C. or miR-181c and or after the addition of extracellular vesicles from cancer cells. mRNA expression in brain endotheli...
ORGANISM(S): Macaca fascicularis 
2015-04-02 | E-GEOD-63447 | biostudies-arrayexpress
Sort   by:  
 Page size