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MetabolomicsNon-targeted LC–MS metabolomics of human left atrial appendage tissue with high vs low myocardial micro(nano)plastic burden

Non-targeted metabolomics profiling was performed on human left atrial appendage tissue obtained from cardiac surgery patients. Samples were grouped by myocardial nanoplastic (NP) burden (High vs Low). Polar metabolites were analyzed by UHPLC–Orbitrap MS in both positive and negative ionization m...

2026-03-28 | MTBLS14056 | MetaboLights
MetabolomicsEnvironmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: A pilot untargeted metabolomic approach
Not available
ORGANISM(S): Homo sapiens 
ST001407 | MetabolomicsWorkbench
MetabolomicsEnvironmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: A pilot untargeted metabolomic approach (part-II)
Not available
ORGANISM(S): Homo sapiens 
ST001406 | MetabolomicsWorkbench
TranscriptomicsOxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome
To identify the detailed molecular causes of the mitochondrial dysfunction, oxidative burden and more vulnerable redox balance in Rett mouse hippocampus, we screened for differential gene expression in the hippocampal CA1 subfield of adult male mice. A whole mouse genome microarray was performed to ...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-32870 | biostudies-arrayexpress
GenomicsBurden- driven feedback control of gene expression
Burden- driven feedback control of gene expression
PRJNA418979 | ENA
ProteomicsCharacterizing heterologous protein burden in Komagataella phaffii
In this study, we explore the molecular response of various K. phaffii strains that produce either the human insulin precursor or Mambalgin-1, examining changes in transcription and changes in intra- and extracellular protein levels. Our findings provide valuable insights into the molecular mechanis...
ORGANISM(S): Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris) 
2025-03-12 | PXD055382 | Pride
Komagataella phaffii  heterologous protein production  burden  secretomics  continuous cultivation 
ProteomicsCharacterizing heterologous protein burden in Komagataella phaffii
In this study, we explore the molecular response of various K. phaffii strains that produce either the human insulin precursor or Mambalgin-1, examining changes in transcription and changes in intra- and extracellular protein levels. Our findings provide valuable insights into the molecular mechanis...
ORGANISM(S): Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris) 
2025-03-12 | PXD055378 | Pride
Komagataella phaffii  heterologous protein production  burden  proteomics  continuous cultivation 
ProteomicsHuman myocardial tissue proteomics associated with late gadolinium enhancement burden in hypertrophic cardiomyopathy
This project investigates myocardial tissue proteomic remodeling associated with cardiac magnetic resonance-defined late gadolinium enhancement burden in patients with hypertrophic cardiomyopathy. Myocardial tissue samples were obtained from patients undergoing septal myectomy, and protein abundance...
ORGANISM(S): Homo sapiens (Human) 
2026-07-22 | PXD079292 | Pride
Human myocardial tissue proteomics associated with late gadolinium enhancement burden in hypertrophic cardiomyopathy 
GenomicsAn analysis of the Neoantigen burden in Breast Carcinoma Patients
An analysis of the Neoantigen burden in Breast Carcinoma Patients
PRJNA781916 | ENA
GenomicsCharacterization of tumor mutational burden in LKB1 mutant lung tumors
Characterization of tumor mutational burden in LKB1 mutant lung tumors
PRJNA564852 | ENA
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