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TranscriptomicsThe Sarcoglycan complex is expressed in the cerebrovascular system and is specifically regulated by astroglial Cx30 channels
Astrocytes, the most prominent glial cell type in the brain, send specialized processes called endfeet around blood vessels and express a large molecular repertoire regulating the cerebrovascular system physiology. One of the most striking properties of astrocyte endfeet is their enrichment in gap j...
ORGANISM(S): Mus musculus 
2015-03-03 | E-GEOD-59148 | biostudies-arrayexpress
ProteomicsSupport-vector-machine learning analysis of the human cerebrovascular thrombi proteome: an exploratory study
Mechanical retrieval of thrombotic material from acute ischemic stroke subjects provides a unique entry point for translational research investigations. Here, we resolved the proteomes of cardioembolic and atherothrombotic cerebrovascular human thrombi and applied an articial intelligence routine to...
ORGANISM(S): Homo sapiens (Human) 
2020-11-05 | PXD020398 | Pride
Thrombus Stroke Mechanical thrombectomy Support vector machine learning Mass-spectrometry Neuroradiology Cerebrovascular 
ProteomicsMolecular characterization of the brain peri-infarct region after post-stroke MANF administration
Shotgun proteomics analysis of brain peri-infarct region from rats subjected to ischemic stroke and treated with AAV-MANF or a control AAV-eGFP, compared to each other and to rats subjected to a sham operation.
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2019-05-28 | MSV000083869 | MassIVE
TranscriptomicsCerebrovascular blood microRNA
blood miRNA expression in ischemic stroke compared to controls miRNA expression in blood cells from patients with ischemic stroke were compared to controls with vascular risk factors
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-55937 | biostudies-arrayexpress
GenomicsCerebrovascular p16INK4A expression induces cerebral small vessel disease-related phenotypes
Cerebrovascular p16INK4A expression induces cerebral small vessel disease-related phenotypes
PRJNA1302351 | ENA
ProteomicsGlobal proteomic analysis of extracellular matrix in mouse and human brain highlights association with cerebrovascular disease
The extracellular matrix (ECM), a key interface between the cerebrovasculature and other cells within the neuro-glial-vascular unit , provides structural stability and modulates cell behaviour and signalling. These functions are dependent on ECM protein composition. Since ECM defects may contribute ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-03-11 | PXD020436 | Pride
Ecm Basement membrane Cerebrovascular Matrisome Proteome Extracellular matrix 
GenomicsPD1-mediated microglia assisted cerebrovascular pruning during vascular development.
PD1-mediated microglia assisted cerebrovascular pruning during vascular development.
PRJNA1157222 | ENA
ProteomicsLuminal cerebrovascular proteomic changes during aging
The blood-brain barrier (BBB) is highly specialized to protect the brain from harmful circulating factors in the blood and maintain brain homeostasis. However, during aging and neurodegenerative disease, the BBB undergoes numerous molecular changes that can promote inflammation and disease pathogene...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-17 | PXD043964 | Pride
Brain Mouse Vasculature Bbb Aging 
GenomicsTranscriptome profiling of cerebrovascular fragments in chow fed vs HFD fed mice.
Transcriptome profiling of cerebrovascular fragments in chow fed vs HFD fed mice.
PRJNA1126237 | ENA
GenomicsTemporally Distinct Myeloid Cell Reponses Mediate Damage and Repair After Cerebrovascular Injury.
Temporally Distinct Myeloid Cell Reponses Mediate Damage and Repair After Cerebrovascular Injury.
PRJNA678288 | ENA
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