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ProteomicsA ChIRP-MS analysis of HOTAIR in HeLa
We employed ChIRP in combination with proteomic strategy to systematically discover HOTAIR-interacting proteins. Three independent biological replicates of ChIRP-MS experiment were performed, alongside negative controls.
ORGANISM(S): Homo sapiens (Human) 
2021-07-09 | PXD015546 | Pride
Hotair hela chirp-ms 
ProteomicsXIST CHIRP-MS in GM12878 and K562 cell line
Identification of cell type-specific XIST co-factors during maintenance of X chromosome inactivation by XIST CHIRP-MS
ORGANISM(S): Homo sapiens (Human) 
2021-03-08 | PXD023516 | Pride
Chirp-ms 
ProteomicsChIRP-MS of long non-coding RNA HOTAIR
Accumulating evidence highlights the role of long non-coding RNAs (lncRNA) in cellular homeostasis, and their dysregulation in disease settings. Most lncRNAs function by interacting with proteins or protein complexes. While several orthogonal methods have been developed to identify these proteins, e...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD029057 | Pride
Lncrna Hotair Chirp-ms 
TranscriptomicsLncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [ChIRP-seq]
While thousands of long non-coding RNAs (lncRNAs) are expressed in higher eukaryotes, the potential regulatory roles of lncRNAs in regulated gene transcription programs remain rather poorly understood. Here, we report that two lncRNAs highly overexpressed in aggressive prostate cancer, PRNCR1 and PC...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-47804 | biostudies-arrayexpress
GenomicsSox2 is present in RNA binding complexes and interacts with snRNA 7SK in mouse embryonic stem cells
Sox2 is a master transcriptional regulator of embryonic development and has been found to interact with RNA binding proteins such as the non-coding RNA 7SK. 7SK has been shown to regulate transcription at regulatory regions, which could suggest a functional interaction with Sox2 for chromatin recrui...
ORGANISM(S): Mus musculus 
2019-05-07 | E-MTAB-7570 | biostudies-arrayexpress
GenomicsKCNQOT1 ChIRP seq and perturbation epigentic profiles [ChIRP]
KCNQOT1 ChIRP seq and perturbation epigentic profiles [ChIRP]
PRJNA858014 | ENA
GenomicsGenomic maps of lincRNA occupancy reveal principles of RNA-chromatin interactions.
Long intergenic noncoding RNAs (lincRNAs) are key regulators of chromatin state, yet the nature and sites of RNA-chromatin interaction are mostly unknown. Here we introduce Chromatin Isolation by RNA Purification (ChIRP), where tiling oligonucleotides retrieve specific lincRNAs and bound protein and...
ORGANISM(S): Drosophila 
2011-09-29 | E-GEOD-31332 | biostudies-arrayexpress
GenomicsGenome-wide map of long non-coding RNA steroid receptor RNA activator (SRA) and its associated RNA heliase p68 in human pluripotent stem cells NTERA2
We performed Chromatin Isolation by RNA Purification (ChIRP) of SRA and ChIP of p68 following by high-throughput sequencing in NTERA2 cell line. We find that SRA localizes with p68 genome-wide at genes whose function is involved in embryonic development. SRA ChIRP and p68 ChIP of triplicate samples.
ORGANISM(S): Homo sapiens 
2014-06-18 | E-GEOD-58641 | biostudies-arrayexpress
TranscriptomicsOpposing roles for the lncRNA Haunt and its genomic locus in regulating HOXA gene activation during embryonic stem cell differentiation
Long noncoding RNAs (lncRNAs) have been implicated in controlling various aspects of embryonic stem cell (ESC) biology, although the functions of specific lncRNAs, and the molecular mechanisms through which they act, remain unclear. Here, we demonstrate discrete and opposing roles for the lncRNA tra...
ORGANISM(S): Mus musculus 
2015-04-20 | E-GEOD-58514 | biostudies-arrayexpress
UnknownThe reliability and validity of a non-wearable indoor positioning system to assess mobility in older adults: A cross-sectional study.
Not available
S-EPMC12027111 | biostudies-literature
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