chromatin remodelling complex

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Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK (1)
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Gregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Dr. Bohr-Gasse 3, Vienna, Austria Current address: AIT Austrian Institute of Technology, Center for Health & Bioresources, Bioresources, Konrad Lorenz Strasse 24, 3430 Tulln, Austria (1)
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IMB, Ackermannweg 4, 55128 Mainz (1)
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Institute of Medical Sciences University of Aberdeen Foresterhill Aberdeen AB25 2ZD Scotland UK (1)
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MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, EH4 2XU, UK (1)
Max Planck Institute for Terrestrial Microbiology Karl-von-Frisch Str. 10 35043 Marburg Germany (1)
Medical Mycology Laboratory, Biology department, Maynooth University, Co. Kildare, Ireland (1)
Medical Research Council - London Institute of Medical Sciences, Telomere Replication and Stability Group, United Kingdom. (1)
Mendel Center for Plant Genomics and Proteomics, Central European Institute of Technology, Brno, Czech Republic (1)
Murdoch Children's Research Institute, Melbourne, VIC, Australia (1)
PROFESSOR JOHN RASKO, AO BSc(Med), MBBS(Hons), PhD, MAICD, FFSc(RCPA), FRCPA, FRACP, FAHMS Head of Department, Cell & Molecular Therapies, Royal Prince Alfred Hospital, Professor, Faculty of Medicine & Health, The University of Sydney, Head, Gene and Stem Cell Therapy Program, Centenary Institute. Level 2, Building 89, Missenden Road, CAMPERDOWN NSW 2050, AUSTRALIA Tel 02 95656160 | Fax 02 9565 6101 | j.rasko@centenary.org.au‌ (1)
Professor of Chemical Structural Biology Director, Centre for Targeted Protein Degradation School of Life Sciences, University of Dundee JBC, Dow Street, Dundee DD1 5EH, UK (1)
Protein Analysis Unit ZfP BioMedical Center, LMU Munich Grosshaderner Strasse 9 82152 Planegg-Martinsried Tel. +49 89 2180 75420 (1)
Proteomic Mass Spectrometry, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK. (1)
School of Life Sciences, University of Nottingham Nottingham UK (1)
The Institute of Cancer Research, London (1)
WCCB, University of Edinburgh (1)
Walter and Elisa Hall Institute of Medical Research Inflammation Division (1)

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IDH1 Reprograms Nucleotide Metabolism by Inducing Chromatin Remodeling and DHODH Transcription to Drive Chemoresistance in Nasopharyngeal Carcinoma

Metabolic reprogramming under therapeutic stress may represent a targetable vulnerability for cancer treatment. Elucidation of the metabolic alterations linked to chemotherapy in nasopharyngeal carcinoma (NPC) could uncover potential therapeutic strategies. Using proteomics and transcriptomic pro...

2026-01-14 | MTBLS11531 | MetaboLights

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

Pulmonary carcinoids are rare neuroendocrine tumours of the lung. The molecular alterations underlying the pathogenesis of these tumours have not been systematically studied so far. Here we perform gene copy number analysis (n¼54), genome/exome (n¼44) and transcriptome (n¼69) sequencing of pulmonary...

EGAS00001000650 | EGA

AP-MS MudPIT run of Ino80 complex

File name explanation: Sc_Ino80_TAP_V2_P1_Ti_101: Sc = Saccharomyces cerevisiae (specie) Ino80 = bait protein TAP = tag V2 = lab instrument name(Velos_Elite2) P1 = biological replicate 1 Ti = LysC+Trypsin digestion 101 = MudPIT run 1 from 1st technical replicate

ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932)

2015-01-28 | MSV000079018 | MassIVE

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

ATP-dependent chromatin remodeling complexes have been shown to participate in DNA replication in addition to transcription and DNA repair. However, the mechanisms of their involvement in DNA replication remain unclear. Here, we reveal a specific function of the yeast INO80 chromatin remodeling comp...

ORGANISM(S): Saccharomyces cerevisiae

2010-06-20 | E-GEOD-18570 | biostudies-arrayexpress

Extensive Chromatin Remodeling and Establishment of Transcription Factor 'Hotspots' during Early Adipogenesis

Adipogenesis is tightly controlled by a complex network of transcription factors acting at different stages of differentiation. Peroxisome proliferator-activated receptor gamma (PPAR gamma) and CCAAT/enhancer binding protein (C/EBP) family members are key regulators of this process. We have employ...

ORGANISM(S): Mus musculus

2011-03-22 | E-GEOD-27826 | biostudies-arrayexpress

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and children. However, DNA copy number and gene expression signatures indicate differences between adult and paediatric cases. To explore the genetic events underlying this distinction, we sequenced the exomes of 48 paediatric GBM samp...

EGAS00001000226 | EGA

The INO80 chromatin remodeling complex regulates histone H2A.Z mobility and the G1-S transition in oligodendrocyte precursors

This project explores the role of the chromatin remodelling complex in oligodendrogial development using a series of tools including conditional disruption of the INO80 gene within mice and primary oligodendrocyte precursors. This experiment sought to understand whether INO80 complex proteins inter...

ORGANISM(S): Mus musculus (Mouse)

2025-05-07 | PXD056438 | Pride

Histone H2B ubiquitylation represses gametogenesis by opposing RSC-Dependent chromatin remodeling at the ste11 master regulator locus

Chromatin modifications play a pivotal role in cell fate decision. In fission yeast, the ste11 gene encodes the master regulator initiating the switch from vegetative growth to gametogenesis when cells starve. The methylation of H3K4 by Set1-COMPASS and consequent promoter nucleosome deacetylation w...

ORGANISM(S): Schizosaccharomyces pombe

2016-07-22 | E-GEOD-80524 | biostudies-arrayexpress

Regulation of retinal development by a Casz1 chromatin remodelling complex

PRJNA523435 | ENA

Ino80 chromatin remodeling complex promotes recovery of stalled replication forks

This SuperSeries is composed of the following subset Series: GSE9233: Genome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae GSE9420: Genome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae Keywords: SuperSeries Refer to individual Series

ORGANISM(S): Saccharomyces cerevisiae

2008-04-10 | E-GEOD-9421 | biostudies-arrayexpress

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