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MetabolomicsA molecular index for biological age identified from the metabolome and senescence-associated secretome in humans.
Unlike chronological age, biological age is a strong indicator of health of an individual. However, the molecular fingerprint associated with biological age is ill-defined. To define a high-resolution signature of biological age, we analyzed metabolome, circulating senescence-associated secretome (S...
2024-01-24 | MTBLS1991 | MetaboLights
ProteomicsComprehensive proteomic characterization of the pectoralis major at three chronological ages in Beijing-You chicken
Chronological age is one of the important factors influencing muscle development and meat quality in chickens. To evaluate the protein expression profiles during skeletal muscle development, we performed a tandem mass tag (TMT)-based quantitative proteomic strategy in pectoralis major (breast muscle...
ORGANISM(S): Gallus gallus (Chicken) 
2021-09-10 | PXD023871 | Pride
Beijing-you chicken  pectoralis major  chronological age  tmt-based quantitative proteomic analysis  parallel reaction monitoring 
TranscriptomicsFunctional Comparison of Chronological and In Vitro Aging: Differential Role of the Cytoskeleton and Mitochondria in Mesenchymal Stromal Cells
Mesenchymal stromal cells (MSCs) are of high relevance for the regeneration of mesenchymal tissues such as bone and cartilage. The promising role of MSCs in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age, t...
ORGANISM(S): Rattus norvegicus 
2013-01-05 | E-GEOD-36596 | biostudies-arrayexpress
TranscriptomicsAge-related behaviors have distinct transcriptional profiles in C. elegans
There has been a great deal of interest in identifying potential biomarkers of aging (Butler et al. 2004). Biomarkers of aging would be useful to predict potential vulnerabilities in an individual that may arise well before they are chronologically expected, due to idiosyncratic aging rates that occ...
ORGANISM(S): Caenorhabditis elegans 
2008-09-16 | E-GEOD-12290 | biostudies-arrayexpress
GenomicsMethylation Array Signals are Predictive of Chronological Age Without Bisulfite Conversion
Methylation Array Signals are Predictive of Chronological Age Without Bisulfite Conversion
PRJNA1181903 | ENA
GenomicsMultiplexing and massive parallel sequencing of targeted DNA methylation to predict chronological age
Multiplexing and massive parallel sequencing of targeted DNA methylation to predict chronological age
PRJNA1113996 | ENA
GenomicsGenome-wide Profiles of DNA Damage Represent Highly Accurate Predictors of Chronological Age
Genome-wide Profiles of DNA Damage Represent Highly Accurate Predictors of Chronological Age
PRJNA1000908 | ENA
ProteomicsChronological mitochondrial proteomics of chemically induced hepatocellular carcinoma in rat
Although disruption of mitochondrial function has been associated with energetic deregulation in cancer, the chronological changes in mitochondria during cancer development remain unclear. With the aim to assess the role of mitochondria throughout cancer development, we analyzed samples chronologica...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-09 | PXD023388 | Pride
Omics integration Shotgun proteomics Rat Hepatocellular carcinoma Chronological study Mitochondria 
ProteomicsAge prediction from human blood plasma using proteomic and small RNA data: a comparative analysis
Aging clocks, built from comprehensive molecular data, have emerged as promising tools in medicine, forensics, and ecological research. However, few studies have compared the suitability of different molecular data types to predict age in the same cohort and whether combining them would improve pred...
ORGANISM(S): Homo sapiens (Human) 
2023-07-03 | PXD028295 | Pride
Human Plasma Mrm-ms 
UnknownAssessing thyroid health: phenotypic age compared to chronological age.
Not available
S-EPMC12270862 | biostudies-literature
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