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GenomicsBradyrhizobium sp. cir1 isolate:HAMBI 3577
Bradyrhizobium sp. cir1 isolate:HAMBI 3577 Genome sequencing and assembly
PRJNA580872 | ENA
TranscriptomicsIdentification of global gene expression in cir1 and cir1:ein2 plants
The Arabidopsis mutant cir1 displayed constitutive expression of defence genes and enhanced resistance to the virulent pathogens Pseudomonas syringae pv tomato (Pst) and Peronospora parasitica Noco2. In order to dissect the downstream signalling components constitutively activated in cir1, cir1 pla...
ORGANISM(S): Arabidopsis thaliana 
2003-10-30 | E-NASC-7 | biostudies-arrayexpress
UnknownThe iron-responsive, GATA-type transcription factor Cir1 influences mating in Cryptococcus neoformans.
Not available
S-EPMC3906865 | biostudies-literature
UnknownIron influences the abundance of the iron regulatory protein Cir1 in the fungal pathogen Cryptococcus neoformans.
Not available
S-EPMC3200532 | biostudies-literature
TranscriptomicsHapX positively and negatively regulates the transcriptional response to iron deprivation in Cryptococcus neoformans
Analysis of the transcriptional response of C. neoformans WT, cir1 mutant, hap3 mutant and hapX mutant to different iron sources. The following experimental design was adopted for the study. Within each strain, each treatment pair (low-iron, +FeCl3, +Transferrin and +Hemin; 6 pairs) were hybridized ...
ORGANISM(S): Cryptococcus neoformans 
2011-04-13 | E-GEOD-22988 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed genes of cir1 mutants in low iron or high iron medium
Iron overload is known to exacerbate many infectious diseases and, conversely, iron withholding is an important defense strategy for mammalian hosts. The mechanisms by which fungal pathogens sense iron in the mammalian host environment are poorly understood. The AIDS-associated pathogen Cryptococcus...
ORGANISM(S): Cryptococcus deneoformans B-3501A Cryptococcus deneoformans 
2006-09-14 | GSE5341 | GEO
GenomicsCharacterizing the transcriptional role of L-DOPA and antimycin A on mitichondrial regulation in Cryptococcus neoformans using a cir1 knockout strain
Characterizing the transcriptional role of L-DOPA and antimycin A on mitichondrial regulation in Cryptococcus neoformans using a cir1 knockout strain
PRJNA922535 | ENA
TranscriptomicsCharacterizing the transcriptional role of L-DOPA and antimycin A on mitichondrial regulation in Cryptococcus neoformans using a cir1 knockout strain
Proper mitochondrial function is critical for the ability of the fungal pathogen Cryptococcus neoformans to cause disease. Mitochondrial dysfunction of WT cells treated with antimycin A or L-DOPA, or on cells lacking Cir1 is evident from this dataset. These experiments revealed influences on transcr...
ORGANISM(S): Cryptococcus neoformans H99 
2024-04-07 | GSE222564 | GEO
GenomicsCryptococcus deneoformans B-3501A
Differentially expressed genes of cir1 mutants in low iron or high iron medium
PRJNA96195 | ENA
ProteomicsThe Role of Core Virulence Kinase Bud32 in Iron Homeostasis Regulation in Cryptococcus neoformans
The core virulence kinase Bud32, which is critical for lung and brain infections, influences the production of major virulence factors in Cryptococcus neoformans, including capsule formation, melanin production, and growth at 37°C. This study explores the role of Bud32 in regulation of iron homeosta...
ORGANISM(S): Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) 
2025-07-23 | PXD056845 | Pride
Bud32  grx4  cir1  hapx  rim101 
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