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TranscriptomicsThe transcriptional profile of deoxycholate-induced sporulation in Clostridium perfringens food poisoning isolate
Clostridium perfringens type A is a common source of food poisoning in humans. Vegetative cells sporulate in the small intestinal tract and produce a major pathogenic factor, C. perfringens enterotoxin (CPE) during sporulation. Although sporulation plays a critical role in the pathogenesis of food p...
ORGANISM(S): Clostridium perfringens 
2016-03-13 | E-GEOD-69649 | biostudies-arrayexpress
TranscriptomicsTranscriptional Profiling Analysis of Host response to Clostridium perfringens Infection in Broilers
Necrotic enteritis is a disease caused by Clostridium perfringens, which threatens poultry production in the absence of dietary antibiotics. A total number of 144 Ross broilers were reared in 12 pens with each hosting 12 birds. Each 6 pens of birds were fed medicated (bacitracin at 55 ppm) or non-m...
ORGANISM(S): Gallus gallus 
2010-06-25 | E-GEOD-13085 | biostudies-arrayexpress
ProteomicsTargeted Mass Spectrometry Analysis of Clostridium perfringens Toxins
Clostridium perfringens is an anaerobic, gram-positive, spore-forming bacterium spread throughout the environment. This bacterium is a common agent in the gastrointestinal tracts of healthy human beings and other mammals. Simultaneously, this agent is one of the most significant producers of toxins ...
ORGANISM(S): Clostridium perfringens Clostridium perfringens 
2019-03-25 | PXD012528 | Pride
Prm  clostridium perfringens  protein toxin  epsilon toxin 
TranscriptomicsVirR and RevR regulate many Clostridium perfringens genes in a reciprocal manner
We further characterize the VirSR and RevR regulatory networks by profiling the C. perfringens strain JIR325 and its isogenic virR and revR regulatory mutants using strand-specific RNA-seq. Two independent biological replicates were sequenced for each strain, generating more than 90 million sequence...
ORGANISM(S): Clostridium perfringens 
2016-08-03 | E-GEOD-72137 | biostudies-arrayexpress
TranscriptomicsTranscriptome of a malO deletion mutant of Clostridium perfringens during stationary phase growth.
The MalNO is a putative two-component signal transduction system, previously known as the VirJI sytem. MalO is the putative cognate response regulator of the MalN sensor histidine kinase. Based on previous evidence that suggested the plc gene, encoding ?-toxin, was upregulated during stationary ph...
ORGANISM(S): Clostridium perfringens str. 13 
2014-12-22 | E-GEOD-28699 | biostudies-arrayexpress
ProteomicsTMT labeled Comparative Proteomic Analysis Reveals Active Immune Response during Clostridium perfringens type C Infected Piglet Diarrhea
We performed a TMT labeling-based quantitative spleen proteomic analysis of the control group (SC), tolerance group (SR) and susceptible group (SS) to identify the differentially expressed proteins (DEPs), and screened potential molecular markers of piglet spleen tissues in response to C. perfringen...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-05-20 | PXD030745 | Pride
Tmt labeling  proteome  clostridium perfringens type c  piglet diarrhea  immune response  spleen 
TranscriptomicsGene expression profiling of Clostridium Perfringens infection in broilers on medicated and non-medicated diets.
Gene expression profiling of clostridium perfringens infection in broilers on medicated and non-medicated diets using chicken 44k agilent microarray. To elucidate molecular and ceelular mechanisms of bacitracin effect on CP infection in chickens by microarray technology. A total number of 600 Ross b...
ORGANISM(S): Gallus gallus 
2009-09-01 | E-GEOD-14759 | biostudies-arrayexpress
TranscriptomicsBroiler responses to virulent and avirulent Clostridium perfringens
Purpose: Analyze gene expression during C. perfringens colonization in the chicken Transcriptomic profile of mRNA from C. perfrinegns from in vivo and in vitro conditions were determined in biological duplicates by RNA-Seq using Illumina HiSeq 2500 Comparison of gene expression through RNA sequenci...
ORGANISM(S): Clostridium perfringens 
2015-10-30 | E-GEOD-70701 | biostudies-arrayexpress
GenomicsClostridium perfringens
Clostridium perfringens Genome sequencing
PRJNA1229601 | ENA
TranscriptomicsTranscritptome of a reeS deletion mutant of Clostridium perfringens during exponential phase growth.
ReeS, previously named as CPE1512, was originally annotated as the only hybrid sensor histidine kinase/response regulator in Clostridium perfringens. Further evidence suggests that ReeS is more likely to function as an orphan sensor histidine kinase. A reeS deletion mutant was constructed and the ...
ORGANISM(S): Clostridium perfringens str. 13 
2013-08-31 | E-GEOD-36786 | biostudies-arrayexpress
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