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GenomicsTranscriptome profiling of colitis-associated colorectal cancer
Transcriptome profiling of colitis-associated colorectal cancer
PRJNA1542567 | ENA
TranscriptomicsGene expression profiling of colitis-associated and sporadic colorectal tumors in mice
To uncover molecular mechanisms specifically involved in the pathogenesis of colitis-associated colon cancer (CAC), we studied tumorigenesis in experimental models of CAC and sporadic CRC that mimic characteristics of human CRC. Using comparative whole genome expression profiling, we observed differ...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-43338 | biostudies-arrayexpress
ProteomicsIntegrated Metabolomics and Proteomics Analysis Reveals the Mechanisms of Banxia-Xiexin Decoction in Colitis-Associated Colorectal Cancer
Colitis-associated colorectal cancer (CAC), a subtype of colorectal cancer arising from chronic colonic inflammation, remains without specific therapeutic agents. Banxia-Xiexin decoction (BXD), a traditional Chinese medicine, is clinically used to treat gastritis and ulcerative colitis; however, its...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD065556 | Pride
Banxia-xiexin decoction  colitis-associated colorectal cancer  serum metabolomics  proteomics  coagulation cascade 
ProteomicsMechanisms research on Huangqin Tang interference with colitis associated colorectal cancer
Although the exact molecular mechanisms of colitis associated col orectal cancer are not fully understood, the chronic inflammation positively correlated with tumorigenesis. The Traditional Chinese Medicine botanical formulation Huangqin Tang has significant anti-inflammatory effects. We investigate...
ORGANISM(S): Mus Musculus 
2022-02-16 | PXD031696 |
TranscriptomicsTranscription profiling of human ulcerative colitis samples to develop a molecular marker
Samples were taken from either surgically resected specimens or during surveillance colonoscopic examination. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be u...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3629 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of colitis-associated colorectal cancer
Bulk RNA sequencing was used to investigate inflammatory signaling in ulcerative colitis and colitis-associated colorectal cancer. The dataset contains 24 tissue libraries across four groups: normal rectum, active ulcerative colitis rectum, colitis-associated colorectal cancer, and non-cancerous rec...
ORGANISM(S): Homo sapiens 
2026-10-11 | GSE350397 | GEO
TranscriptomicsExpression data for the different phases of ulcerative colitis-associated carcinogenesis in a mouse model
Nonresolving inflammation is correlated to carcinogenesis. Ulcerative colitis-associated colorectal cancer (UC-CRC), one of the typical carcinoma generated by inflammation that cannot be resolved properly, has been widely believed to involve a multistep process contains M-bM-^@M-^\inflammation-dyspl...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-31106 | biostudies-arrayexpress
TranscriptomicsDeletion of TNF in Winnie-ApcMin/+ mice reveals its dual role in the onset and progression of colitis-associated colorectal cancer
Colorectal cancer (CRC) is among the best examples depicting the relationship between inflammation and increased cancer risk. The introduction of new therapeutic options targeting the inflammatory mediators has been shown to markedly decrease the overall risk of CRC even though their chemopreventive...
ORGANISM(S): Mus musculus 
2023-05-01 | E-MTAB-12356 | biostudies-arrayexpress
GenomicsThe evolutionary history of human colitis-associated colorectal cancer
Inflammatory bowel disease confers an increased lifetime risk of developing colorectal cancer (CRC), and colitis-associated CRC (CA-CRC) is molecularly distinct from sporadic CRC (S-CRC). Here we have dissected the evolutionary history of CA-CRC using multi-region sequencing. Exome sequencing was p...
EGAS00001003028 | EGA
GenomicsCardamonin repel colitis and its associated colorectal cancer
Cardamonin repel colitis and its associated colorectal cancer
PRJNA497866 | ENA
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