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TranscriptomicsGene Expression Profiling In Murine Corneal Neovascularization Models
In order to find out the vital genes during the corneal neovascularization (CNV), we set up two CNV models, one being induced by suture placement and the other by alkali burn to the corneal center. Young adult Balb/c and C57BL/6 were used. The corneas were checked daily for CNV development and some ...
ORGANISM(S): Mus musculus 
2011-02-08 | E-GEOD-23347 | biostudies-arrayexpress
ProteomicsExploring Corneal Neovascularization: An Integrated Approach Using Transcriptomics and Proteomics in an Alkali Burn Mouse Model
Purpose Corneal neovascularization (CNV) impairs corneal transparency and visual acuity. The study aims to deepen our understanding of the molecules involved in CNV induced by alkali burns, facilitate a better grasp of CNV mechanisms, and uncover potential therapeutic targets. Methods Mice were sele...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD047367 | Pride
Transcriptomics  proteomics  alkali burns  corneal neovascularization  mice  lcp1  csrp2  tgm2  tgfbi 
GenomicsPerturbation of epithelial and limbal stem cell identity in pathologic corneal neovascularization
Perturbation of epithelial and limbal stem cell identity in pathologic corneal neovascularization
PRJNA1248564 | ENA
UnknownCorneal stromal stem cell-derived extracellular vesicles inhibit corneal neovascularization.
Not available
S-EPMC12947098 | biostudies-literature
UnknownThree kinds of corneal host cells contribute differently to corneal neovascularization.
Not available
S-EPMC6604366 | biostudies-literature
UnknownCXCR3 deletion aggravates corneal neovascularization in a corneal alkali-burn model.
Not available
S-EPMC10191246 | biostudies-literature
UnknownCorneal neovascularization during experimental fungal keratitis.
Not available
S-EPMC2756518 | biostudies-literature
TranscriptomicsPerturbation of epithelial and limbal stem cell identity in pathologic corneal neovascularization
We have employed a single cell sequencing approach using 10x Genomics scRNAseq to study a corneal suture model that damages the epithelium and induces sustained inflammation and neovascularization, focusing on the impact to limbal epithelial stem cells. Additionally, we evaluated the potential of du...
ORGANISM(S): Mus musculus 
2026-08-03 | GSE294213 | GEO
TranscriptomicsRNA-seq of choroid and retina in tree shrews with choroidal neovascularization
In order elucidate the key signaling pathways in choroidal neovascularization, we induced choroidal angiogenesis by laser photocoagulation in 12 tree shrews and obtained mRNA profiles of their choroids and retinas by high-throughput transcriptome sequencing. Gene ontology(GO) and kyoto encyclopedia ...
ORGANISM(S): Tupaia chinensis 
2021-03-21 | E-MTAB-10198 | biostudies-arrayexpress
UnknownGenome Editing VEGFA Prevents Corneal Neovascularization In Vivo.
Not available
S-EPMC11220714 | biostudies-literature
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