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GenomicsDual RNA-seq identifies proteins and pathways required for Clostridioides difficile colonisation
Dual RNA-seq identifies proteins and pathways required for Clostridioides difficile colonisation
PRJEB60050 | ENA
ProteomicsIntegrated transcriptomic and proteomic analysis of Tritipyrum provides insights into the molecular basis of salt tolerance
Soil salinity is a major environmental stress that restricts crop growth and yield. Here, crucial proteins and biological pathways were investigated under salt-stress and recovery conditions in Tritipyrum “Y1805” to explore its salt-tolerance mechanism. In total, 44 and 102 differentially expressed ...
ORGANISM(S): Triticum aestivum (Wheat) 
2021-12-08 | PXD026671 | Pride
Tritipyrum  salt stress  recovery  proteome  transcriptome  crucial proteins and pathways 
ProteomicsTMT-Based Quantitative Proteomic Analysis Reveals the Crucial Biological Pathways Involved in Brain Injury Induced by Chest Exposure to Shock Waves
Long term chest blast exposure can lead to mental disorders, brain inflammation and oxidative stress in soldiers. However, the underlying mechanism of brain injury caused indirectly by chest blast remains unclear. It is urgent to find more potential biomarkers to reveal the deeper pathogenesis of th...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-30 | PXD025204 | Pride
Chest blast  brain injury  tandem mass spectrometry quantitative proteomics  inflammation  signaling pathways 
TranscriptomicsBronchial Airway Gene Expression in Smokers with Lung or Head and Neck Cancer
Cigarette smoking is the major cause of cancers of the respiratory tract, including non-small cell lung cancer (NSCLC) and head and neck cancer (HNC). In order to better understand carcinogenesis of the lung and upper airways, we have compared the gene expression profiles of tumour-distant, histolog...
ORGANISM(S): Homo sapiens 
2014-05-24 | E-MTAB-1690 | biostudies-arrayexpress
TranscriptomicsZebrafish Zili- and Ziwi-interacting small RNAs
Small RNAs exert an effect through diverse RNA interference pathways to transcriptionally or post-transcriptionally silence their targets. The Piwi-interacting RNAs (piRNAs) represent a germline-specific small RNA pathway where Piwi proteins themselves are thought to mediate piRNA biosynthesis. Here...
ORGANISM(S): Danio rerio 
2008-11-04 | E-GEOD-12547 | biostudies-arrayexpress
ProteomicsDNA methylation impacts soybean early development by modulate hormones and metabolic pathways
Genomic DNA methylation patterns play a crucial role in the developmental processes of plants and mammals. In this study, we aimed to investigate the significant effects of epigenetic mechanisms on the development of soybean seedlings and metabolic pathways. Our analyses show that 5-azaC-treatment a...
ORGANISM(S): Glycine max 
2026-05-05 | PXD068592 | Pride
Rddm 5-azac Abiotic and biotic stress Carbon and nitrogen assimilation Epigenetic control Glycine max Polyamines metabolism 
UnknownProteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome.
Not available
S-EPMC11527607 | biostudies-literature
ProteomicsTMT-Based Quantitative Proteomic Analysis Reveals the Crucial Biological Pathways Involved in Brain Injury Induced by Chest Exposure to Shock Waves
Long term chest blast exposure can lead to mental disorders, brain inflammation and oxidative stress in soldiers. However, the underlying mechanism of brain injury caused indirectly by chest blast remains unclear. It is urgent to find additional reliable biomarkers to reveal the intimate details of ...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD026015 | Pride
Chest blast  brain injury  tandem mass spectrometry quantitative proteomics  inflammation  signaling pathways 
ProteomicsHypoxia induced sex-difference in zebrafish brain proteome profile reveals the crucial role of H3K9me3 in recovery from acute hypoxia
Understanding the molecular basis of sex differences in neural response to acute hypoxic insult has profound implications for the effective prevention and treatment of ischemic stroke. Global hypoxic-ischemic induced neural damage has been studied recently under the well-controlled, non-invasive, re...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-02-22 | PXD027528 | Pride
Ipa Sex difference Pathway analysis Itraq Hypoxia-ischemia recovery 
UnknownIdentification of crucial genes and pathways associated with colorectal cancer by bioinformatics analysis.
Not available
S-EPMC7039150 | biostudies-literature
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