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ProteomicsThe chromatin assembly factor complex 1 (CAF1) and 5-Azacytidine (5-AzaC) affect cell motility in Src-transformed human epithelial cells
Tumor invasion into surrounding stromal tissue is a hallmark of high-grade, metastatic cancers. Oncogenic transformation of human epithelial cells in culture can be triggered by activation of v-Src kinase, resulting in increased cell motility, invasiveness and tumorigenicity and provides a valuable ...
ORGANISM(S): Homo sapiens (Human) 
2016-12-20 | PXD005494 | Pride
Epigenetics Proteomics Invasion 
TranscriptomicsImmunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting.
Cytokine genes are targets of multiple epigenetic mechanisms in T lymphocytes. 5-azacytidine (5-azaC) is a nucleoside-based DNA methyltransferases (DNMT) inhibitor which induces demethylation and gene reactivation. In the current study, we analyzed the effect of 5-azaC in T-cell function and observe...
ORGANISM(S): Homo sapiens 
2009-09-02 | GSE17922 | GEO
TranscriptomicsTranscription profiling of murine neurosphere cultures carrying a Bcl2 transgene and treated with histone deacetylase inhibitor Trichostatin A and demethylating agent AzaC to study DNA methylation and histone deacetylation in neural stem cells.
Neurosphere cultures were established from individually isolated E 14.5 forebrains of mouse embryos that carry a bcl2 transgene. Single-cell suspensions were prepared, seeded at 1x105 cells/ml and treated for two days with 150 nM Trichostatin A (TSA; histone deacetylase inhibitor), 500 nM 5-Aza-2-de...
ORGANISM(S): Mus musculus 
2007-12-19 | E-GEOD-587 | biostudies-arrayexpress
UnknownTranscriptome profiling of 'Kyoho' grape at different stages of berry development following 5-azaC treatment.
Not available
S-EPMC6839162 | biostudies-literature
UnknownThe anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities.
Not available
S-EPMC6039303 | biostudies-literature
UnknownEffect of DNA methylation, modified by 5-azaC, on ecophysiological responses of a clonal plant to changing climate.
Not available
S-EPMC9568541 | biostudies-literature
UnknownEffects of 5-azaC on Iridoid Glycoside Accumulation and DNA Methylation in Rehmannia glutinosa.
Not available
S-EPMC9260266 | biostudies-literature
Unknown5-AzaC Facilitates Somatic Embryogenesis and Germination Across Two Embryogenic Lines in <i>Larix olgensis</i>.
Not available
S-EPMC12473665 | biostudies-literature
GenomicsSchistosoma mansoni
5-AzaC effect on Schistosoma mansoni Transcriptome
PRJNA428470 | ENA
GenomicsHomo sapiens
Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting.
PRJNA119883 | ENA
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