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ProteomicsComparative proteomic analysis identifies differentially expressed proteins associated with meiotic arrest in cattle-yak hybrids
Comparative proteomic analysis identified a total of 452 differentially abundant proteins (DAPs) in the fluorescence-activated cell sorting (FACS) isolated spermatocytes from 12-month-old yak and cattleyak. 291 proteins were only identified in yak spermatocytes. Gene Ontology analysis revealed that ...
ORGANISM(S): Bos Mutus 
2023-03-21 | PXD043039 |
UnknownDNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities.
Not available
S-EPMC3909494 | biostudies-literature
UnknownBreak-induced replication requires DNA damage-induced phosphorylation of Pif1 and leads to telomere lengthening.
Not available
S-EPMC4199488 | biostudies-literature
UnknownDNA double-strand break end resection factors and WRN facilitate mitotic DNA synthesis in human cells.
Not available
S-EPMC12379236 | biostudies-literature
UnknownArabidopsis DNA polymerase lambda mutant is mildly sensitive to DNA double strand breaks but defective in integration of a transgene.
Not available
S-EPMC4444747 | biostudies-literature
UnknownCHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair.
Not available
S-EPMC11762318 | biostudies-literature
UnknownA Cyclin-Dependent Kinase Inhibitor, Dinaciclib, Impairs Homologous Recombination and Sensitizes Multiple Myeloma Cells to PARP Inhibition.
Not available
S-EPMC4747838 | biostudies-literature
TranscriptomicsCellular stress, inflammation and barrier damage in gut epithelial cells caused by aspartame
Aspartame has been widely used as a sweetener in foods and beverages since the 1980s. In this study, we aimed to assess the effect of aspartame on gut epithelial cell biology, inflammation, and the epithelial barrier. Aspartame shows cytotoxic effects and epithelial barrier damage as well as proinfl...
ORGANISM(S): Homo sapiens 
2026-01-01 | GSE285905 | GEO
UnknownTyrosyl-DNA phosphodiesterases are involved in mutagenic events at a ribonucleotide embedded into DNA in human cells.
Not available
S-EPMC7775084 | biostudies-literature
ProteomicsProteome profiling of HaCaT keratinocytes
An important step in the proteomic analysis is the optimal extraction and the processing of protein material in order to ensure the highest sensitivity in downstream protein detection. Cell lysis is important for proteomic profiling with an eventual aim to discover differently expressed proteins (DE...
ORGANISM(S): Homo sapiens (Human) 
2022-07-20 | PXD035202 | Pride
Lc-ms/ms  searchgui  double-strand break repair via break-induced replication pathway  mcm family Hacat keratinocytes  sodium dodecyl sulfate  1de-gel concentration  osmotic shock 
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